- Basic information
- CohesinDB ID: CDBP00417234
- Locus: chr21-33189336-33190586
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Data sourse: GSE206145, GSE116344
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Cell type: RH4, HEK293T
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 38%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZSCAN5C, NME2, XBP1, FOXA1, TFAP4, BMI1, INSM2, ZFP64, ZBTB44, ZNF189, MYOG, ZNF629, TEAD1, KLF10, ESR1, ZNF561, ZNF577, CTCF, EP300, ZBTB20, TRIM24, ZNF528, KMT2B, PDX1, GLIS1, POU5F1, BRD3, ZNF317, ZBTB17, ZBTB48, DUX4, ERG, ZBTB21, MYC, ONECUT1, SMARCA4, GRHL3, NKX2-1, GABPA, NKX3-1, ZNF639, NR3C1, ZNF85, KMT2A, EZH2, FEZF1, SPI1, KLF17, GATA2, BCL6, NKX2-2, EZH2phosphoT487, ZNF335, ZFX, CBX8, ZNF18, PRDM10, ZNF549, ZNF384, ZNF35, OSR2, ZNF184, ARNT, PRDM9, MAFB, ZXDB, PIAS1, BCL11A, SP1, ZNF479, OVOL3, HOXA9, PCGF2, PHIP, FOXP1, PRDM6, ZNF34, FOXA2, ZNF600, ZNF692, ZSCAN16, WT1, ZNF30, ZNF574, CDK9, HOXB13, ZIC2, HIF1A, OTX2, TAL1, MAX, GATA1, CBX2, SP7, TP53, ZNF213, ZNF334, PHOX2B, AR, ZBTB40, ZBTB42, RNF2, NCOR1, SCRT1, BRD4, ZSCAN23, ZNF24
- Target gene symbol (double-evidenced CRMs): IFNGR2,AP000311.1,CRYZL1,EVA1C,IFNAR1,TMEM50B,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops
- Related gene:
ENSG00000166979,
ENSG00000159082,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
ENSG00000249209,
ENSG00000205758,
- Related loop:
chr21:32400000-32425000~~chr21:33175000-33200000,
chr21:32650000-32675000~~chr21:33175000-33200000,
chr21:32675000-32700000~~chr21:33175000-33200000,
chr21:32825000-32850000~~chr21:33175000-33200000,
chr21:32850000-32875000~~chr21:33175000-33200000,
chr21:32900000-32925000~~chr21:33175000-33200000,
chr21:32925000-32950000~~chr21:33175000-33200000,
chr21:32975000-33000000~~chr21:33175000-33200000,
chr21:33175000-33200000~~chr21:33350000-33375000,
chr21:33175000-33200000~~chr21:33425000-33450000,
chr21:33175000-33200000~~chr21:33600000-33625000,