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Basic information

CohesinDB ID: CDBP00417235

Locus: chr21-33191132-33191643

Data sourse: ENCSR000BLD, GSE67783, GSE98367, GSE206145, GSE120943

Cell type: RPE, H1-hESC, Monocytes, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 35%, "13_ReprPC": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF239, ZNF621, ZFX, ZSCAN21, ZNF473, ZNF662, DDX5, MCM2, PHB2, HDGF, PBX1, ZNF148, EHMT2, ZNF2, ZBTB5, RUNX3, ZBTB10, ZNF311, HMBOX1, PAX5, ZNF398, ZSCAN26, ZNF639, CBX2, KMT2A, ZNF544, ESR1, MED, ZNF571, BCL6B, ZNF146, MYNN, RNF2, SALL1, TCF3, ZNF776, SALL2

Target gene symbol (double-evidenced CRMs): AP000311.1,EVA1C,SYNJ1,CRYZL1,IFNAR1,TMEM50B,IFNGR2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 30

Related genes and loops

Related gene: ENSG00000166979, ENSG00000159082, ENSG00000142166, ENSG00000159128, ENSG00000142188, ENSG00000249209, ENSG00000205758,

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Deatailed information for cohesin site CDBP00417235