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Basic information

CohesinDB ID: CDBP00417242

Locus: chr21-33211272-33213452

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, GSE165895, GSE126634, ENCSR879KXD, ENCSR000BLS, GSE105028, GSE206145-NatGen2015, ENCSR054FKH, GSE55407, GSE62063, ENCSR153HNT, GSE83726, GSE116344, ENCSR917QNE

Cell type: H1-hESC, Fibroblast, RH4, Hep-G2, HFFc6, THP-1, Ramos, K-562, Liver, HAP1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.878

Subunit: NIPBL,SA1,Rad21,SMC1,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 34%, "7_Enh": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, FOSL1, HMG20A, MEIS2, XBP1, FOXA1, PBX2, UBTF, RXRB, KDM3A, TFAP4, HDGF, LYL1, THRB, ZFP64, CHD7, RUNX3, MXD4, SMARCE1, TP63, ZNF467, JMJD1C, MYOG, TEAD1, TRIM28, ELF1, RBM39, ETV1, NFE2L2, KLF6, RCOR2, LMO2, HNF1B, TP73, CTCF, TCF12, JUN, EP300, E4F1, ARID5B, LMO1, GATA6, SOX5, PAX8, DPF2, DMAP1, TRIM24, SOX6, RAD51, E2F1, TEAD4, FOXA3, ZNF175, GATAD2A, EHMT2, MLX, PDX1, RBPJ, EED, CHD8, ZNF263, MYCN, CDK7, ID3, POU5F1, CTBP1, MTA2, ZBTB17, DUX4, STAT1, GATAD1, SAP130, NBN, HNF4G, ERG, NFKB2, ETS1, MYC, SMARCA4, ARID1B, HOMEZ, RAD21, FOXP2, NKX2-1, FOXK2, GABPA, ZNF614, XRCC5, IKZF1, RCOR1, LEF1, MIER3, NFE2, NR2F6, TEAD2, VDR, ESRRA, CEBPB, NFRKB, KMT2A, CREB1, CCAR2, TBL1XR1, ZNF652, GABPB1, ELF4, SPI1, TFE3, MIXL1, HDAC2, GATA2, ZNF644, MXD3, FLI1, DRAP1, ZGPAT, NR2C2, SMARCA5, NFIL3, ZIM3, ETV5, RUNX1, THAP11, BCL6, SMC1A, HDAC1, CEBPA, SOX13, ZFX, FIP1L1, SP5, SMARCC1, RARA, ZNF384, NOTCH1, NFYC, BRD9, RUNX2, ZNF184, ARNT, ZNF48, HMGB2, HMBOX1, ZEB2, SMAD4, CBFA2T3, ETV6, NR2C1, FOS, HMGXB4, CDK8, MED1, TEAD3, CEBPD, MYB, SCRT2, L3MBTL2, EVI1, SP1, HNF4A, IKZF5, NKX2-5, ZBTB7A, ARID2, ATF7, BCOR, TCF3, FOXP1, SMC3, MLLT1, HMGB1, SKI, CBFA2T2, PPARG, CBX3, FOXA2, MTA3, MEIS1, CREM, MIER2, WT1, ZBTB33, CDK9, ZNF580, KDM1A, YY1, RELA, ZNF589, JUNB, NEUROD1, TCF4, ZFP36, OTX2, GATA3, TAL1, MAX, SPIB, GATA1, MTA1, ZNF143, HAND2, CEBPG, BCL11B, GFI1B, NR2F2, NR2F1, NEUROG2, TP53, NFKB1, MYOD1, ELF3, KAT8, TBX21, ARID4B, BHLHE40, NFKBIZ, ZBTB40, ZBTB26, NCOR1, NOTCH3, BRD4, JUND, RNF2, ILF3, SCRT1, MAZ, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): AP000311.1,TMEM50B,ITSN1,RCAN1,SON,DONSON,IFNGR2,CRYZL1,AP000295.1,ATP5PO,SMIM11A,IFNAR1,IL10RB

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000249624, ENSG00000243646, ENSG00000142166, ENSG00000159128, ENSG00000142188, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000205670, ENSG00000159200,

eachgene

Deatailed information for cohesin site CDBP00417242