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Basic information

CohesinDB ID: CDBP00417244

Locus: chr21-33219732-33220309

Data sourse: GSE67783, GSE126755, ENCSR153HNT

Cell type: K-562, Neutrophil, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 81%, "14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX3, CREM, ZFX, ETS1, NFIC, ATF3, ATF4, ATF2, GABPA, MAX, ELF1, CREB1, C11orf30, GABPB1, JUN, ZHX2, CTCF, SPI1, IRF4, BRD4, JUND, E2F1, ATF1, ZNF316

Target gene symbol (double-evidenced CRMs): RCAN1,AP000295.1,SMIM11A,ATP5PO,ITSN1,IFNGR2,DONSON,IFNAR1,AP000311.1,TMEM50B,SON,CRYZL1,IL10RB

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000249624, ENSG00000243646, ENSG00000142166, ENSG00000159128, ENSG00000142188, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000205670, ENSG00000159200,

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Deatailed information for cohesin site CDBP00417244