- Basic information
- CohesinDB ID: CDBP00417245
- Locus: chr21-33222873-33223242
-
Data sourse: GSE206145, GSE206145-NatGen2015, GSE206145-GSE177045, ENCSR153HNT
-
Cell type: K-562, Fibroblast, MCF-7, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 80%,
"14_ReprPCWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CEBPB, OGG1, CEBPA, TRIM28, TOP2A, SP140, ARNT, BRD4, RXRA, PKNOX1, ZBTB48, SETDB1, PAX5, SPI1, ZFP28
- Target gene symbol (double-evidenced CRMs): IFNAR1,AP000311.1,SON,IL10RB,CRYZL1,RCAN1,DONSON,TMEM50B,ATP5PO,ITSN1,AP000295.1,IFNGR2,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000243646,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
ENSG00000159200,
- Related loop:
chr21:29300000-29325000~~chr21:33200000-33225000,
chr21:33200000-33225000~~chr21:33300000-33325000,
chr21:33200000-33225000~~chr21:33325000-33350000,
chr21:33200000-33225000~~chr21:33350000-33375000,
chr21:33200000-33225000~~chr21:33375000-33400000,
chr21:33200000-33225000~~chr21:33400000-33425000,
chr21:33200000-33225000~~chr21:33425000-33450000,
chr21:33200000-33225000~~chr21:33450000-33475000,
chr21:33200000-33225000~~chr21:33550000-33575000,
chr21:33200000-33225000~~chr21:33575000-33600000,
chr21:33200000-33225000~~chr21:33600000-33625000,
chr21:33200000-33225000~~chr21:33800000-33825000,
chr21:33200000-33225000~~chr21:33875000-33900000,
chr21:33200000-33225000~~chr21:33900000-33925000,
chr21:33200000-33225000~~chr21:34350000-34375000,
chr21:33200000-33225000~~chr21:34600000-34625000,
chr21:33200000-33225000~~chr21:42225000-42250000,
chr21:33225000-33250000~~chr21:33425000-33450000,
chr21:33225000-33250000~~chr21:33875000-33900000,