Deatailed information for cohesin site CDBP00417252

Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00417252
  • Locus: chr21-33246774-33247187
  • Data sourse: ENCSR153HNT, GSE98367
  • Cell type: K-562, Macrophage
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: SA1,SMC1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 93% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 62%, "6_EnhG": 20%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, HMG20A, LCORL, ZNF496, SOX2, NME2, XBP1, FOXA1, HLF, PBX2, RXRB, KDM3A, TFAP4, HNRNPK, HDGF, LYL1, ATF3, NFIC, THRB, RUNX3, PRDM1, CHD7, MXD4, MECOM, ZSCAN4, JMJD1C, MAF, TEAD1, TRIM28, BCLAF1, RCOR2, ESR1, MLL, LMO2, CTCF, JUN, TCF12, EP300, ARID5B, LMO1, MNT, GATA6, SOX5, TRIM24, FOXA3, GATAD2A, MLX, EED, RBPJ, POU2F2, CHD8, NANOG, POU5F1, CDK7, RUNX1T1, ZBTB48, STAT1, SRF, SAP130, ARID3A, HNF4G, ERG, PBX1, SMARCC2, ETS1, MYC, ONECUT1, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, FOXK2, GABPA, ZNF614, XRCC5, IKZF1, MIER3, NR2F6, ARNTL, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, EZH2, TBL1XR1, ZNF652, SPI1, MIXL1, ZNF664, HDAC2, GATA2, ZNF644, FLI1, DRAP1, ZGPAT, NFIL3, NCOA2, ETV5, RUNX1, THAP11, SMC1A, BCL6, CEBPA, SOX13, ZFX, POU4F2, MYBL2, RARA, NOTCH1, RUNX2, CDK6, GATA4, ARNT, ZNF48, PRDM9, SMAD4, PBX3, SUPT5H, CDK8, MED1, TEAD3, CEBPD, MYB, SMAD1, EVI1, RBM22, USF1, BCL11A, SP1, NR4A1, HNF4A, IKZF5, REST, RBM25, ASH2L, TCF3, FOXP1, SMC3, MLLT1, STAG1, SKI, MEF2B, PPARG, FOXA2, CBX3, CREM, MEIS1, MIER2, GTF2B, WT1, ZBTB33, MEF2C, CDK9, HOXB13, ZKSCAN1, ZNF580, KDM1A, YY1, RELA, NEUROD1, KAT2B, TCF4, OTX2, GATA3, TAL1, MAX, GATA1, ZNF143, CEBPG, NR2F2, TCF7L2, NEUROG2, PKNOX1, MED, ZNF334, PHF5A, ELF3, KAT8, T, TBX21, ARID4B, AR, NFKBIZ, ZBTB26, NOTCH3, BRD4, JUND, CLOCK, CUX1
  • Target gene symbol (double-evidenced CRMs): ATP5PO,IFNAR2,TMEM50B,AP000311.1,ITSN1,IFNGR2,AP000295.1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 155
  • Number of somatic mutations (non-coding): 31
  • Related genes and loops
  • Related gene: ENSG00000249624, ENSG00000159110, ENSG00000159128, ENSG00000142188, ENSG00000249209, ENSG00000205726, ENSG00000241837,
  • Related loop: chr21:27500000-27525000~~chr21:33250000-33275000, chr21:33225000-33250000~~chr21:33425000-33450000, chr21:33225000-33250000~~chr21:33875000-33900000, chr21:33250000-33275000~~chr21:33350000-33375000,
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