- Basic information
- CohesinDB ID: CDBP00417254
- Locus: chr21-33248634-33250562
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Data sourse: GSE67783, GSE98367, GSE62063, GSE120943, ENCSR153HNT
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Cell type: Monocytes, K-562, HSPC, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 55%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, BCL6, SMC1A, ZNF496, RUNX1T1, ZFX, XBP1, ZSCAN5A, STAT1, DDX5, CDK9, LEO1, EZH1, CDK6, MYC, ARID1B, GRHL3, NKX2-1, PRDM9, TAL1, CBFA2T3, GATA1, ZNF143, NR2F6, MED1, STAT5B, NR2F2, MYB, ELF1, NR2F1, TRIM28, CTCF, RBM22, SPI1, BCL11A, GATA2, BRD4, SCRT1, TCF3, SMC3, EED
- Target gene symbol (double-evidenced CRMs): IFNGR2,ATP5PO,IFNAR2,TMEM50B,AP000295.1,ITSN1,IFNAR1,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 110
- Number of somatic mutations (non-coding): 22
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
- Related loop:
chr21:27500000-27525000~~chr21:33250000-33275000,
chr21:33225000-33250000~~chr21:33425000-33450000,
chr21:33225000-33250000~~chr21:33875000-33900000,
chr21:33250000-33275000~~chr21:33350000-33375000,