- Basic information
- CohesinDB ID: CDBP00417255
- Locus: chr21-33251697-33253100
-
Data sourse: GSE138405, GSE67783, GSE86191, GSE98367
-
Cell type: Hela-Kyoto, HCT-116, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SMC3,Rad21,SA1,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"4_Tx": 63%,
"5_TxWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CEBPA, ZBTB17, STAT1, FOXA1, LEO1, HOXB13, ATF3, MYC, ATF2, GABPA, STAT3, SUPT5H, CEBPB, ESR1, L3MBTL2, CTCF, RBM22, SPI1, ATF7, MYNN, BRD4, E2F1
- Target gene symbol (double-evidenced CRMs): IFNAR1,AP000295.1,IFNAR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 215
- Number of somatic mutations (non-coding): 43
- Related genes and loops