- Basic information
- CohesinDB ID: CDBP00417258
- Locus: chr21-33257059-33258358
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Data sourse: GSE67783, ENCSR153HNT, GSE86191, GSE98367
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Cell type: K-562, HCT-116, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 51%,
"5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, MEF2B, CHD8, MAFG, TBL1X, EBF1, TOP2A, NFATC1, ZFX, ZNF600, MTA2, XBP1, DUX4, MAFF, WT1, ZBTB33, LEO1, HOXB13, RELA, CREBBP, NEUROD1, JUNB, MYC, CDK6, SMARCA4, GRHL3, HIF1A, ARNT, OTX2, ZNF519, BATF, ZSCAN5D, STAT3, XRCC5, FOS, SUPT5H, IKZF1, MITF, MED1, VDR, BCL6, MAF, NCOA3, TRIM28, MYB, TFAP2C, NR2F1, ZNF3, ESR1, TP53, OCA2, C11orf30, NFKB1, JUN, RBM22, CTCF, BCL11A, MAFK, TBX21, BHLHE40, AR, BAF155, POU2F3, ZNF567, JUND, BRD4, TCF3, NOTCH3, NFYB, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): IFNAR2,IFNAR1,AP000295.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 65
- Number of somatic mutations (non-coding): 0
- Related genes and loops