- Basic information
- CohesinDB ID: CDBP00417259
- Locus: chr21-33259241-33262524
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Data sourse: ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE103477, GSE111537, GSE25021, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR917QNE, GSE67783, GSE86191, GSE206145-NatGen2015, GSE120943, GSE116344, GSE98367, ENCSR000BLS, GSE206145, GSE62063, GSE55407, ENCSR167MTG, ENCSR000HPG, ENCSR054FKH, GSE68388, GSE50893
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Cell type: MDM, RH4, GM19240, Liver, HuCC-T1, RPE, GM2630, Fibroblast, IMR-90, HFFc6, SNYDER, Monocytes, GM2588, SK-N-SH, GM19239, THP-1, Macrophage, Ramos, HCT-116, Hep-G2, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.756
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 51%,
"7_Enh": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF362, TOP2A, DDX5
- Target gene symbol (double-evidenced CRMs): IL10RB,IFNAR1,IFNAR2,AP000295.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 155
- Number of somatic mutations (non-coding): 31
- Related genes and loops