- Basic information
- CohesinDB ID: CDBP00417265
- Locus: chr21-33278760-33279199
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Data sourse: GSE206145-NatGen2015, GSE62063, GSE98367
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Cell type: Fibroblast, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,Mau2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 34%,
"4_Tx": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, FOXA2, ZSCAN5D, SOX2, ZFX, POU4F2, XBP1, GTF2B, FOXA1, BAHD1, LEO1, SP4, HOXB13, TWIST1, KDM1A, ERG, RELA, JUNB, MYC, CDK6, GATA4, GRHL3, PRDM9, ZNF354A, PAX5, ZNF449, SUPT5H, ZNF143, RCOR1, SPIB, NR3C1, CEBPB, TEAD1, TRIM28, ZNF680, ZNF331, PIAS1, ZNF217, PKNOX1, SETDB1, CTCF, ZNF507, SPI1, GATA6, EGLN2, RBM25, FLI1, BRD4, ZNF528, ZNF280A, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): AP000295.1,SMIM11A,URB1,IL10RB,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000249624,
ENSG00000243646,
ENSG00000205670,
- Related loop:
chr21:27500000-27525000~~chr21:33250000-33275000,
chr21:32375000-32400000~~chr21:33275000-33300000,
chr21:32450000-32475000~~chr21:33275000-33300000,
chr21:33250000-33275000~~chr21:33350000-33375000,
chr21:33275000-33300000~~chr21:34350000-34375000,