- Basic information
- CohesinDB ID: CDBP00417271
- Locus: chr21-33297831-33303232
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Data sourse: ENCSR000BLD, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE121355, GSE73207, GSE103477, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, GSE93080, ENCSR000DZP, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, GSE206145-NatGen2015, GSE120943, ENCSR703TNG, GSE106870, GSE116344, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR879KXD, ENCSR000BLS, GSE206145, GSE85526, ENCSR000ECE, GSE62063, ENCSR000BMY, ENCSR000EHX, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE110061, GSE129526, GSE111913, GSE155324, GSE38411, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE50893, GSE126755, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM10847, GM2610, CVB-hiPSC, GM19240, HSPC, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, Fibroblast, HEKn, HeLa-S3, BCBL-1, K-562, GM18486, DKO, H1-hESC, SNYDER, Monocytes, GM18505, Lymphoblast, TF-1, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19193, THP-1, GM19099, Macrophage, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, HL-60, Hep-G2, HCAEC, GM19238, HeLa, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 26% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.478
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 34%,
"7_Enh": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF384, NEUROD1, EBF1, BRD4, DUX4, OTX2, MAZ, ZNF770
- Target gene symbol (double-evidenced CRMs): EVA1C,SMIM11A,URB1,IFNAR2,IL10RB,AP000295.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 14
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000166979,
ENSG00000249624,
ENSG00000159110,
ENSG00000243646,
ENSG00000205670,
- Related loop:
chr21:32375000-32400000~~chr21:33275000-33300000,
chr21:32450000-32475000~~chr21:33275000-33300000,
chr21:32825000-32850000~~chr21:33300000-33325000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:33200000-33225000~~chr21:33300000-33325000,
chr21:33207409-33208640~~chr21:33308059-33310267,
chr21:33275000-33300000~~chr21:34350000-34375000,