- Basic information
- CohesinDB ID: CDBP00417274
- Locus: chr21-33307849-33310424
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Data sourse: GSE72082, ENCSR000FAD, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE108869, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE143937, ENCSR000BKV, GSE138405, GSE116344, ENCSR703TNG, GSE98367, ENCSR879KXD, ENCSR000EHW, GSE62063, ENCSR000BMY, ENCSR000EHX, ENCSR167MTG, ENCSR000EDE, ENCSR153HNT, GSE83726, GSE50893
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Cell type: RH4, GM2610, GM19240, H9-hESC, GM2630, GM12890, HeLa-S3, GM2255, K-562, GM18486, GM18526, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19099, Macrophage, MCF-7, GM12892, Ramos, Hela-Kyoto, Hep-G2, GM19238
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 12% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.711
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 51%,
"7_Enh": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF248, SCRT1, NFE2, ZNF316
- Target gene symbol (double-evidenced CRMs): AP000295.1,IFNAR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops