- Basic information
- CohesinDB ID: CDBP00417277
- Locus: chr21-33315634-33316528
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Data sourse: GSE116344, GSE62063, GSE98367
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Cell type: RH4, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 68%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NANOG, MYCN, SIN3A, ZNF534, XBP1, CBX8, ZNF28, PBX1, ASCL1, BMI1, RUNX2, NFIC, MYC, RAD21, HIF1A, CBFB, PRDM9, STAT3, MAX, PAX5, ZNF143, CDK8, IKZF1, MED1, TEAD1, TRIM28, EZH2, TP53, ESR1, TP73, ZNF334, MYOD1, CTCF, ZHX2, PAX3-FOXO1, AR, SIX2, RNF2, NOTCH3, BRD4, TCF3, E2F1, TEAD4, MYF5
- Target gene symbol (double-evidenced CRMs): IFNAR2,AP000295.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops