- Basic information
- CohesinDB ID: CDBP00417278
- Locus: chr21-33316892-33318449
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Data sourse: GSE98367, ShirahigeLab-NatGen2015, GSE120943, ENCSR153HNT, GSE103477
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Cell type: MDM, Fibroblast, Monocytes, K-562, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 66%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CHD8, SMC1A, CEBPA, PPARG, ZFX, ZNF317, MAFF, STAT1, CBX8, YY1, RELA, BMI1, MYC, SMARCA4, MCM3, RAD21, HIF1A, RXRA, HMBOX1, FOS, CDK8, MED1, NR3C1, CEBPB, JMJD1C, TRIM28, KMT2A, EZH2, ESR1, OCA2, C11orf30, ZNF334, NFKB1, CTCF, MAFK, SPI1, SP1, IRF1, RXR, INTS13, ZNF777, RNF2, BRD4, PCGF2, ZNF316
- Target gene symbol (double-evidenced CRMs): IFNAR2,AP000295.1
- Function elements
- Human SNPs: Narcolepsy
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops