- Basic information
- CohesinDB ID: CDBP00417280
- Locus: chr21-33321044-33321781
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Data sourse: GSE67783, GSE98367, GSE110061, GSE206145-NatGen2015, ENCSR153HNT, GSE131577
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Cell type: Fibroblast, HCT-116, HL-60, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SMC1,SA1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 72%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, CHD4, NR3C1, BCL11B, PGR, HDAC2, BCL6, ZSCAN5D, SSRP1, ZFX, IKZF2, BRD4, WT1, CTCF, ZBTB48, ZBTB33, ARID3A, ZHX2, IKZF1, HNRNPK
- Target gene symbol (double-evidenced CRMs): IFNAR1,AP000295.1,IFNAR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
- Related loop:
chr21:32825000-32850000~~chr21:33300000-33325000,
chr21:32925000-32950000~~chr21:33325000-33350000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33200000-33225000~~chr21:33300000-33325000,
chr21:33200000-33225000~~chr21:33325000-33350000,
chr21:33325000-33350000~~chr21:33425000-33450000,
chr21:33325000-33350000~~chr21:33450000-33475000,