Deatailed information for cohesin site CDBP00417281

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  • Basic information
  • CohesinDB ID: CDBP00417281
  • Locus: chr21-33322068-33327091
  • Data sourse: ENCSR230ZWH, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR917QNE, GSE93080, GSE67783, GSE86191, GSE101921, ENCSR806UKK, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE38411, ENCSR000BLD, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE76893, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE62063, ENCSR807WAC, ENCSR981FDC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR153HNT, GSE68388, GSE126990
  • Cell type: MDM, RH4, GM10847, GM2610, SLK, GM19240, OCI-AML-3, HSPC, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, HEKn, THP-1, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, Macrophage, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, Neutrophil, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 55% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.311
  • Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 91% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "1_TssA": 25%, "2_TssAFlnk": 21%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: HDAC2, ZC3H8, IKZF2, FOXA1, RELB, CTCF, ZHX2, IKZF1
  • Target gene symbol (double-evidenced CRMs): AP000295.1,IFNAR1,IFNGR2,IFNAR2,TMEM50B
  • Function elements
  • Human SNPs: Multiple_sclerosis
  • Number of somatic mutations (coding): 28
  • Number of somatic mutations (non-coding): 48
  • Related genes and loops
  • Related gene: ENSG00000249624, ENSG00000159110, ENSG00000142166, ENSG00000159128, ENSG00000142188,
  • Related loop: chr21:32825000-32850000~~chr21:33300000-33325000, chr21:32925000-32950000~~chr21:33325000-33350000, chr21:32950000-32975000~~chr21:33300000-33325000, chr21:33025000-33050000~~chr21:33325000-33350000, chr21:33200000-33225000~~chr21:33300000-33325000, chr21:33200000-33225000~~chr21:33325000-33350000, chr21:33325000-33350000~~chr21:33425000-33450000, chr21:33325000-33350000~~chr21:33450000-33475000,
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