- Basic information
- CohesinDB ID: CDBP00417282
- Locus: chr21-33327900-33328437
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Data sourse: ENCSR153HNT, ENCSR000BKV, GSE98367
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Cell type: K-562, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 57%,
"7_Enh": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, ZSCAN5D, POU5F1, HDAC1, SIN3A, NME2, DUX4, FOXA1, ZBTB33, NBN, CREB3L1, CREBBP, ZBTB2, HDGF, EHMT2, RUNX2, SMARCA4, ZNF184, ARID1B, OTX2, GATA3, HMBOX1, MGA, ZEB2, MAX, SMARCE1, GATA1, GMEB1, ZNF592, TEAD1, ZBTB11, ESR1, GRHL2, L3MBTL2, PHOX2B, GABPB1, TFAP2A, DPF2, HDAC2, GATA2, ZBTB40, PAX8, RNF2, MLLT1, TFAP2C
- Target gene symbol (double-evidenced CRMs): IFNAR2,AP000295.1,IFNGR2,TMEM50B,IFNAR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32825000-32850000~~chr21:33300000-33325000,
chr21:32925000-32950000~~chr21:33325000-33350000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33200000-33225000~~chr21:33300000-33325000,
chr21:33200000-33225000~~chr21:33325000-33350000,
chr21:33325000-33350000~~chr21:33425000-33450000,
chr21:33325000-33350000~~chr21:33450000-33475000,