Deatailed information for cohesin site CDBP00417284

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  • Basic information
  • CohesinDB ID: CDBP00417284
  • Locus: chr21-33330820-33332435
  • Data sourse: GSE93080, ENCSR000EAC, GSE67783, ENCSR000BKV, GSE86191, ENCSR000BMY, ENCSR153HNT, GSE50893
  • Cell type: GM12892, GM2630, HCT-116, GM10847, GM18505, GM12878, GM12891, GM12890, GM19238, K-562, GM19239, HSPC, GM18486
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 4% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.856
  • Subunit: NIPBL,SA1,Rad21
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 91% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 31%, "4_Tx": 22%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: ZNF468, CBX5, SOX2, NME2, MEIS2, XBP1, FOXA1, LEO1, PBX2, ZNF529, HDGF, NFIC, RUNX3, PRDM1, ATF4, MORC2, CBFB, ZNF189, SMARCE1, PAX5, MZF1, MITF, ZNF320, KLF5, TRIM28, BCLAF1, ZNF26, ESR1, OCA2, CTCF, TCF12, ZNF577, EP300, E4F1, JUN, ZNF507, DPF2, IRF4, TRIM24, SOX6, ZNF528, ZNF280A, TEAD4, EHMT2, TFAP2C, EED, NANOG, CHD8, POU2F2, ZSCAN5D, MYCN, ZNF263, BRD3, ID3, XRCC3, CTBP1, MTA2, ZNF317, ZBTB48, STAT1, NBN, TBP, ZNF300, ERG, ZNF597, SMARCC2, ZNF626, MYC, MIER1, SMARCA4, RFX1, ARID1B, OGG1, GRHL3, FOXK2, IKZF1, RCOR1, TERF2, LEF1, ZNF639, KMT2A, EZH2, KLF8, FEZF1, SPI1, HDAC2, GATA2, SMARCA5, HCFC1R1, ZIM3, ETV5, CC2D1A, SMC1A, CBX1, HDAC1, LDB1, CRY1, AFF4, ZFX, ZNF549, NSD2, PRDM10, MEF2A, MYBL2, NOTCH1, BRD9, RUNX2, CDK6, OSR2, ZNF184, ARNT, PRDM9, ZEB2, HMBOX1, ZNF518A, PBX3, CBFA2T3, FOXM1, SUPT5H, CDK8, ETV6, MED1, GMEB1, TERF1, ZNF558, MYB, PIAS1, ZNF3, NCOA1, L3MBTL2, SETDB1, RBM22, USF1, BCL11A, SP1, ZBTB7A, HNRNPLL, TCF3, SMC3, STAG1, MLLT1, NFATC3, TRP47, CBFA2T2, MEF2B, FOXA2, TBL1X, CBX3, CREM, NFATC1, PAF1, MTA3, GTF2B, WT1, ZBED1, ZNF30, MEF2C, ZBTB33, CDK9, HOXB13, BCL3, MPHOSPH8, KDM1A, YY1, RELA, CHAMP1, ZNF510, ZNF610, SP140, TCF4, HIF1A, SKIL, BHLHE22, MGA, TAL1, MAX, ZNF143, GATA1, KLF4, SP7, NCOA3, NR2F2, PKNOX1, ZNF334, MYOD1, TBX21, AR, ZBTB40, ZNF324, ZNF280D, HSF1, RNF2, NOTCH3, BRD4, NCOR1, MYNN, CLOCK, ZNF24, ZNF316
  • Target gene symbol (double-evidenced CRMs): IFNAR2,AP000295.1,TMEM50B,IFNGR2,IFNAR1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 5
  • Number of somatic mutations (non-coding): 5
  • Related genes and loops
  • Related gene: ENSG00000249624, ENSG00000159110, ENSG00000142166, ENSG00000159128, ENSG00000142188,
  • Related loop: chr21:32925000-32950000~~chr21:33325000-33350000, chr21:33025000-33050000~~chr21:33325000-33350000, chr21:33200000-33225000~~chr21:33325000-33350000, chr21:33325000-33350000~~chr21:33425000-33450000, chr21:33325000-33350000~~chr21:33450000-33475000,
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