- Basic information
- CohesinDB ID: CDBP00417287
- Locus: chr21-33334567-33335084
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Data sourse: ENCSR000EAC, ENCSR153HNT
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Cell type: K-562, GM12878
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 57%,
"8_ZNF/Rpts": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: BCL6, CHD8, ZSCAN5D, TBL1X, SMC1A, MYCN, ZNF263, ZFX, POU4F2, XBP1, ZNF660, WT1, ZSCAN5A, ZBTB48, TOP2A, ZBTB33, LEO1, HOXB13, MPHOSPH8, ERG, RELA, ZNF384, ATF3, MYC, ZNF184, ZIC2, HIF1A, ATF2, ZNF189, ZNF143, SUPT5H, SMARCB1, FOS, PLAG1, CDX2, ZNF629, TRIM28, TFAP2C, ZNF791, CREB1, TP53, SETDB1, CTCF, RBM22, JUN, GSPT2, AR, ATF7, BRD4, JUND, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): TMEM50B,IFNAR2,AP000295.1,IFNAR1,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32925000-32950000~~chr21:33325000-33350000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33200000-33225000~~chr21:33325000-33350000,
chr21:33325000-33350000~~chr21:33425000-33450000,
chr21:33325000-33350000~~chr21:33450000-33475000,