- Basic information
- CohesinDB ID: CDBP00417288
- Locus: chr21-33337603-33338145
-
Data sourse: GSE62063, GSE98367
-
Cell type: Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 59%,
"4_Tx": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: AR, CREBBP, RELA, NANOG, CHD8, FOXA2, EZH2, GRHL3, ZSCAN16, ARNT, BRD4, FOXA1, SUPT5H, KDM1A
- Target gene symbol (double-evidenced CRMs): TMEM50B,IFNGR2,AP000295.1,IFNAR2,IFNAR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 11
- Number of somatic mutations (non-coding): 11
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32925000-32950000~~chr21:33325000-33350000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33200000-33225000~~chr21:33325000-33350000,
chr21:33325000-33350000~~chr21:33425000-33450000,
chr21:33325000-33350000~~chr21:33450000-33475000,