- Basic information
- CohesinDB ID: CDBP00417290
- Locus: chr21-33340630-33341347
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Data sourse: GSE62063, GSE98367
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Cell type: Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 58%,
"4_Tx": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, SMC1A, MEF2B, BCL6, FOXA2, EBF1, TOP2A, NFATC1, CEBPA, CHD8, XBP1, GTF2B, ZBTB48, SOX2, STAT1, MEF2C, HOXB13, PRDM10, ERG, MEF2A, YY1, HDGF, ZNF35, RELA, ZNF384, JUNB, ATF3, NFIC, MYC, GATA4, ZNF362, RAD21, RUNX3, PRDM1, SKIL, GRHL3, ATF4, RXRA, ATF2, TAL1, MAX, TP63, SPIB, FOS, CDK8, SUPT5H, CD74, MED1, CEBPG, CEBPB, JMJD1C, BCLAF1, KMT2A, ZNF687, ZNF22, CTCF, ZNF436, JUN, SPI1, TBX21, IRF1, IRF4, TRIM24, ATF7, HOXA9, BRD4, RELB, PRDM6, ZNF528, ZIM3, ZNF554, NCOR2, MLLT1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): IFNGR2,AP000295.1,IFNAR2,TMEM50B,IFNAR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 24
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32925000-32950000~~chr21:33325000-33350000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33200000-33225000~~chr21:33325000-33350000,
chr21:33325000-33350000~~chr21:33425000-33450000,
chr21:33325000-33350000~~chr21:33450000-33475000,