- Basic information
- CohesinDB ID: CDBP00417291
- Locus: chr21-33341696-33343063
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Data sourse: GSE67783, GSE86191, GSE98367, GSE206145-NatGen2015, GSE120943, ENCSR153HNT
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Cell type: Fibroblast, HCT-116, Monocytes, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 54%,
"5_TxWk": 44%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, GLIS1, ZNF426, ZNF697, LDB1, ZFX, XBP1, ZSCAN16, WT1, ZBTB48, ZNF101, FOXA1, ZFP3, ZNF433, ZNF654, ZNF580, ZNF529, AEBP2, ZBTB21, HDGF, ZBTB8A, ZNF341, MYC, ZNF266, ZFP64, ZNF510, SP140, PRDM12, ZNF781, ZSCAN23, ZNF518A, ZNF189, TAL1, GATA1, ZNF639, ZNF629, ZNF558, ZXDB, ZBTB11, ZNF680, ZNF791, ZNF213, ZNF292, ZNF140, CTCF, RBM22, ZNF577, SPI1, ZNF664, AR, ZBTB40, HDAC2, REST, ZNF366, BRD4, FOXP1, ZNF528, ZNF623, ZC3H11A, ZNF555, ZNF34
- Target gene symbol (double-evidenced CRMs): IFNAR2,AP000295.1,TMEM50B,IFNGR2,IFNAR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32925000-32950000~~chr21:33325000-33350000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33200000-33225000~~chr21:33325000-33350000,
chr21:33325000-33350000~~chr21:33425000-33450000,
chr21:33325000-33350000~~chr21:33450000-33475000,