- Basic information
- CohesinDB ID: CDBP00417295
- Locus: chr21-33355143-33356443
-
Data sourse: GSE67783, GSE98367, GSE206145, GSE62063, GSE120943, ENCSR153HNT, GSE83726, GSE116344
-
Cell type: RPE, RH4, Monocytes, K-562, HSPC, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"4_Tx": 58%,
"5_TxWk": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: AR, ERG3
- Target gene symbol (double-evidenced CRMs): SYNJ1,PAXBP1,TMEM50B,CRYZL1,IFNAR2,AP000311.1,AP000295.1,IL10RB,IFNAR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 40
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000159086,
ENSG00000249624,
ENSG00000159110,
ENSG00000243646,
ENSG00000142166,
ENSG00000142188,
ENSG00000249209,
ENSG00000205758,
- Related loop:
chr21:32652779-32654447~~chr21:33360228-33362109,
chr21:32725000-32750000~~chr21:33350000-33375000,
chr21:32825000-32850000~~chr21:33350000-33375000,
chr21:33175000-33200000~~chr21:33350000-33375000,
chr21:33199037-33200983~~chr21:33360047-33362483,
chr21:33199045-33200951~~chr21:33360197-33362875,
chr21:33199050-33200800~~chr21:33360051-33362614,
chr21:33199054-33200784~~chr21:33360453-33362457,
chr21:33199055-33201024~~chr21:33360153-33362582,
chr21:33199061-33200994~~chr21:33360009-33362674,
chr21:33199063-33200997~~chr21:33360045-33362734,
chr21:33199071-33200963~~chr21:33360153-33362100,
chr21:33199075-33200850~~chr21:33360213-33362978,
chr21:33199075-33200916~~chr21:33360017-33362749,
chr21:33199076-33200916~~chr21:33360130-33362524,
chr21:33199079-33200988~~chr21:33360176-33362505,
chr21:33199086-33200764~~chr21:33360477-33362524,
chr21:33199100-33200791~~chr21:33360203-33362100,
chr21:33199124-33200675~~chr21:33360104-33362934,
chr21:33199158-33200742~~chr21:33360558-33362130,
chr21:33200000-33225000~~chr21:33350000-33375000,
chr21:33250000-33275000~~chr21:33350000-33375000,
chr21:33350000-33375000~~chr21:33450000-33475000,
chr21:33350000-33375000~~chr21:33600000-33625000,
chr21:33360009-33362674~~chr21:33444395-33446546,
chr21:33360017-33362749~~chr21:33373161-33376136,
chr21:33360017-33362749~~chr21:33444399-33446509,
chr21:33360045-33362734~~chr21:33444390-33446463,
chr21:33360121-33362991~~chr21:33373327-33376082,
chr21:33360121-33362991~~chr21:33444374-33446510,
chr21:33360130-33362524~~chr21:33444431-33446547,
chr21:33360132-33362704~~chr21:33444396-33446544,
chr21:33360151-33362730~~chr21:33373805-33376073,
chr21:33360151-33362730~~chr21:33443867-33446335,
chr21:33360153-33362582~~chr21:33444393-33446535,
chr21:33360157-33362875~~chr21:33444546-33446097,
chr21:33360173-33362129~~chr21:33444604-33446075,
chr21:33360203-33362100~~chr21:33444407-33446481,
chr21:33360213-33362978~~chr21:33444400-33446333,
chr21:33360224-33362415~~chr21:33444418-33446468,
chr21:33360228-33362109~~chr21:33444451-33446541,
chr21:33360313-33362104~~chr21:33444549-33446058,