- Basic information
- CohesinDB ID: CDBP00417302
- Locus: chr21-33371268-33371854
-
Data sourse: GSE120943, GSE98367
-
Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 78%,
"5_TxWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: POU2F2, CHD8, BCL6, TBL1X, ZNF263, MYCN, CBX1, CBX3, ZFX, MEF2B, XBP1, GTF2B, WT1, ZSCAN5A, ZBTB48, STAT1, ERG, YY1, RELA, CDK6, GRHL3, ZFP36, NKX2-1, ZNF143, TRIM28, SCRT2, EZH2, ZIM3, MED26, ZNF334, SETDB1, CTCF, AR, PAX8, SOX4, EGLN2, HSF1, BRD4, SCRT1, MAZ, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): SYNJ1,CRYZL1,AP000311.1,IFNAR2,IL10RB,AP000295.1,PAXBP1,TMEM50B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000159086,
ENSG00000249624,
ENSG00000159110,
ENSG00000243646,
ENSG00000142188,
ENSG00000249209,
ENSG00000205758,
- Related loop:
chr21:32725000-32750000~~chr21:33350000-33375000,
chr21:32725000-32750000~~chr21:33375000-33400000,
chr21:32825000-32850000~~chr21:33350000-33375000,
chr21:32825000-32850000~~chr21:33375000-33400000,
chr21:32900000-32925000~~chr21:33375000-33400000,
chr21:32925000-32950000~~chr21:33375000-33400000,
chr21:32975000-33000000~~chr21:33375000-33400000,
chr21:33025000-33050000~~chr21:33375000-33400000,
chr21:33175000-33200000~~chr21:33350000-33375000,
chr21:33198398-33200659~~chr21:33373911-33375521,
chr21:33199025-33201086~~chr21:33373747-33375905,
chr21:33199037-33200983~~chr21:33373772-33376036,
chr21:33199045-33200951~~chr21:33373804-33376065,
chr21:33199050-33200800~~chr21:33373781-33376153,
chr21:33199050-33200857~~chr21:33373787-33375924,
chr21:33199055-33201024~~chr21:33373597-33375828,
chr21:33199058-33200673~~chr21:33373965-33375569,
chr21:33199058-33200767~~chr21:33373905-33375710,
chr21:33199059-33200758~~chr21:33373019-33376113,
chr21:33199061-33200994~~chr21:33373693-33376103,
chr21:33199063-33200997~~chr21:33373686-33376129,
chr21:33199063-33201023~~chr21:33373680-33375788,
chr21:33199064-33200992~~chr21:33373698-33376058,
chr21:33199071-33200963~~chr21:33373671-33376017,
chr21:33199075-33200850~~chr21:33373649-33376041,
chr21:33199079-33200988~~chr21:33373770-33375893,
chr21:33199087-33200894~~chr21:33373730-33375882,
chr21:33199094-33200842~~chr21:33373665-33375712,
chr21:33199095-33200896~~chr21:33374154-33375564,
chr21:33199100-33200791~~chr21:33373764-33375895,
chr21:33199124-33200675~~chr21:33373671-33376085,
chr21:33199168-33200811~~chr21:33373895-33375674,
chr21:33199174-33200665~~chr21:33373871-33376085,
chr21:33200000-33225000~~chr21:33350000-33375000,
chr21:33200000-33225000~~chr21:33375000-33400000,
chr21:33250000-33275000~~chr21:33350000-33375000,
chr21:33350000-33375000~~chr21:33450000-33475000,
chr21:33350000-33375000~~chr21:33600000-33625000,
chr21:33360017-33362749~~chr21:33373161-33376136,
chr21:33360121-33362991~~chr21:33373327-33376082,
chr21:33360151-33362730~~chr21:33373805-33376073,
chr21:33375000-33400000~~chr21:33500000-33525000,
chr21:33375000-33400000~~chr21:33525000-33550000,
chr21:33375000-33400000~~chr21:33550000-33575000,
chr21:33375000-33400000~~chr21:33875000-33900000,
chr21:33375000-33400000~~chr21:34350000-34375000,