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Basic information

CohesinDB ID: CDBP00417305

Locus: chr21-33387293-33390415

Data sourse: GSE67783, GSE86191, GSE98367, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, GSE126755

Cell type: RPE, Fibroblast, HCT-116, Monocytes, K-562, Neutrophil, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 53%, "14_ReprPCWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, CTNNB1, SMC1A, MEF2B, FOXA2, BCL6, CEBPA, ZFX, ZBTB17, ZBTB48, STAT1, SRF, MEF2C, ERG, RELA, CREBBP, ATF3, GRHL3, ATF4, MECOM, SPIB, CDK8, NR3C1, CEBPB, CEBPG, KMT2A, SNAI2, ELF3, SP1, SPI1, BCL11A, RXR, BRD4, BCOR, FOXP1

Target gene symbol (double-evidenced CRMs): AP000311.1,SON,SYNJ1,GART,SMIM11A,IFNAR2,PAXBP1,ATP5PO,DONSON,AP000295.1,ITSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 19

Related genes and loops

Related gene: ENSG00000159082, ENSG00000159086, ENSG00000249624, ENSG00000159110, ENSG00000159131, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000205670,

eachgene

Deatailed information for cohesin site CDBP00417305