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Basic information

CohesinDB ID: CDBP00417308

Locus: chr21-33399401-33399800

Data sourse: GSE126755, GSE98367

Cell type: Neutrophil, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC3,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: non-Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 46%, "5_TxWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, NME2, XBP1, FOXA1, HLF, MLL4, ZFHX2, HDGF, LYL1, ZNF90, NFIC, THAP1, CBFB, ZNF189, MECOM, ZSCAN4, TP63, MITF, JMJD1C, KLF5, ELF1, TRIM28, TEAD1, ETV1, KLF6, LMO2, ESR1, TP73, USF2, JUN, TCF12, CTCF, EP300, RFX5, RAD51, SMC1, TEAD4, TFAP2C, EED, GLIS1, ZSCAN5D, MYCN, CTBP1, ZNF317, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ZNF134, ERG2, PAX6, ERG, CHD4, ETS1, MYC, SMARCA4, RAD21, LHX2, RXRA, NKX2-1, STAT3, ZNF614, XRCC5, IKZF1, RCOR1, ARNTL, VDR, NR3C1, CEBPB, STAT5B, KMT2A, EZH2, ZHX2, SPI1, MIXL1, HDAC2, INTS13, GATA2, ZNF644, MXD3, FLI1, RELB, MRTFB, ETV5, RUNX1, BCL6, SMC1A, CEBPA, LDB1, SIN3A, ZFX, SMAD3, ERG3, TWIST1, SMARCC1, ZBTB2, ZNF384, RUNX2, ARNT, DAXX, ZNF48, SMAD4, CBFA2T3, PBX3, ZNF10, FOS, CDK8, MED1, TEAD3, MYB, SCRT2, EVI1, HIF2A, USF1, BCL11A, NIPBL, SP1, REST, ATF7, PHIP, BCOR, TCF3, SMC3, MLLT1, STAG1, SKI, MEF2B, CBX3, MTA3, EBF1, MEIS1, ZNF600, ZSCAN16, WT1, ZBTB33, CDK9, YY1, RELA, NEUROD1, MCM3, HIF1A, OTX2, GATA3, TAL1, MAX, ZNF143, GATA1, PLAG1, GFI1B, NR2F2, TCF7L2, KDM5B, TP53, NFKB1, ELF3, PHF5A, BRD2, TBX21, BHLHE40, AR, TAF1, EGLN2, ZBTB42, HSF1, NCOR1, ZBTB26, BRD4, SCRT1, JUND, MAZ, AHR

Target gene symbol (double-evidenced CRMs): PAXBP1,ATP5PO,IFNAR2,SMIM11A,AP000295.1,GART,ITSN1,DONSON,SON,AP000311.1,IFNGR2,SYNJ1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000159082, ENSG00000159086, ENSG00000249624, ENSG00000159110, ENSG00000159128, ENSG00000159131, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000205670,

eachgene

Deatailed information for cohesin site CDBP00417308