- Basic information
- CohesinDB ID: CDBP00417311
- Locus: chr21-33409784-33417376
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, GSE25021, GSE131606, ENCSR000EDW, ENCSR917QNE, ENCSR000EFJ, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE67783, GSE86191, GSE206145-NatGen2015, GSE120943, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR000BLS, GSE206145, ENCSR635OSG, ENCSR167MTG, ENCSR054FKH, ENCSR153HNT, GSE50893
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Cell type: GM10847, GM2610, GM19240, Liver, RPE, Fibroblast, GM2255, IMR-90, K-562, GM18486, DKO, H1-hESC, Monocytes, GM12878, GM19239, Macrophage, HCT-116, Hep-G2, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.789
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 42%,
"4_Tx": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: VDR, ZNF880, SUPT16H, PRDM1, BRD4, ZBTB48, GATA3, SPI1, ZBTB33, RBFOX2, RBM22, BCL11A, MLLT1, TBX21, YY1
- Target gene symbol (double-evidenced CRMs): IFNGR2,AP000295.1,IFNAR2,SYNJ1
- Function elements
- Human SNPs: Multiple_sclerosis
- Number of somatic mutations (coding): 180
- Number of somatic mutations (non-coding): 0
- Related genes and loops