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Basic information

CohesinDB ID: CDBP00417313

Locus: chr21-33420917-33421930

Data sourse: GSE93080, GSE67783, ENCSR153HNT, GSE98367

Cell type: K-562, GM12878, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 62%, "5_TxWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, BCL6, SMC1A, FOXA2, ZNF263, HMG20A, CEBPA, NFATC1, ZFX, SOX13, MIER2, SMAD3, FOXA1, ZBTB33, LEO1, HOXB13, KDM1A, YY1, RELA, ZNF384, MYC, ZNF184, ZNF24, GRHL3, PBX4, GATA3, SMAD4, APC, SUPT5H, FOS, ZNF736, NR3C1, TEAD3, PML, TEAD1, ZNF3, ESR1, TP53, ZNF22, CTCF, RBM22, KAT8, EP300, ELF4, ZNF664, SOX5, ZBTB40, MRTFB, TEAD4, FOXA3, ZNF175, GATAD2A

Target gene symbol (double-evidenced CRMs): AP000295.1,SYNJ1,IFNAR2,IFNGR2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 114

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159082, ENSG00000249624, ENSG00000159110, ENSG00000159128,

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Deatailed information for cohesin site CDBP00417313