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Basic information

CohesinDB ID: CDBP00417316

Locus: chr21-33427110-33427633

Data sourse: GSE67783, ENCSR153HNT

Cell type: K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 74%, "5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, FOSL1, PGR, FOXA1, LEO1, NFIC, ZNF362, THAP1, RUNX3, SMARCE1, PAX5, TP63, ZNF629, ELF1, BCLAF1, TEAD1, NFE2L2, ESR1, JUN, CTCF, TCF12, BAF155, KLF1, E2F1, SMC1, TFAP2C, EED, POU2F2, ZSCAN5D, MYCN, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ERG, HOXC5, MYC, RFX1, RAD21, GRHL3, NKX2-1, STAT3, XRCC5, DNMT3B, ZNF639, HNRNPH1, NR3C1, CEBPB, KMT2A, CREB1, KLF8, GRHL2, ZHX2, SPI1, EHF, KLF17, HDAC2, GATA2, MXD3, ZNF554, PTBP1, SMC1A, SIN3A, ZFX, SMAD3, TWIST1, ZNF384, ZNF35, ZNF184, NFIB, PBX4, ZNF48, SUPT5H, FOS, MED1, TEAD3, ZEB1, SMAD1, ZNF22, KLF16, RBM22, BCL11A, REST, ZNF479, ARID1A, HNRNPLL, TCF3, SMC3, MLLT1, STAG2, NELFA, CBX3, EBF1, PAF1, ZNF600, ZSCAN16, ZNF692, WT1, HOXB13, YY1, RELA, NEUROD1, JUNB, SP140, OTX2, GATA3, KLF15, BATF, MAX, AGO2, SP7, GFI1B, NR2F2, ZNF687, ZBTB6, NFKB1, AR, BRD4, JUND, SCRT1, CLOCK, MAZ, ZSCAN23, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): AP000295.1,TMEM50B,IFNGR2,IFNAR2,IFNAR1,SYNJ1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 9

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000159082, ENSG00000249624, ENSG00000159110, ENSG00000142166, ENSG00000159128, ENSG00000142188,

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Deatailed information for cohesin site CDBP00417316