Browse_each

Basic information

CohesinDB ID: CDBP00417318

Locus: chr21-33430846-33431848

Data sourse: GSE67783, GSE120943, ENCSR153HNT, GSE98367

Cell type: K-562, Monocytes, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 73%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, CBX5, ZSCAN5C, MEIS2, FOXA1, LEO1, PBX2, TFAP4, HDGF, TSC22D4, BMI1, NFIC, ATF3, ZFP64, RUNX3, CHD7, PRDM1, CBFB, ZNF189, SMARCE1, PAX5, BACH2, MAF, KLF5, ELF1, BCLAF1, ZNF121, ETV1, RBM39, SMAD5, ESR1, MLL, TP73, CTCF, TCF12, JUN, EP300, DPF2, SOX4, IRF4, TRIM24, SOX6, RAD51, E2F1, SMC1, TEAD4, KMT2B, GTF2F1, RBPJ, EED, POU2F2, MYCN, POU5F1, TOP2A, ID3, MTA2, ZBTB48, ZSCAN5A, MLLT3, NBN, ARID3A, ERG, HOXC5, CHD4, ZNF597, ZNF341, ETS1, MYC, SMARCA4, ARID1B, RAD21, FOXP2, GRHL3, PHF21A, RXRA, FOXK2, BATF3, GABPA, STAT3, IKZF1, RCOR1, DNMT3B, GFI1, ZNF639, VDR, CD74, NR3C1, CEBPB, KMT2A, CREB1, GRHL2, EBF3, SPI1, EHF, IRF1, GATA2, GATAD2B, FLI1, MXI1, SMARCA5, RELB, MRTFB, NCOA2, ZNF554, ATF1, RUNX1, SMC1A, CEBPA, HDAC1, SIN3A, ZFX, SMAD3, ERG3, TRIM22, SMARCC1, MEF2A, ZBTB2, TAF15, ZNF184, PBX4, BACH1, ARNT, ATF2, ZEB2, HMBOX1, ETV6, FOXM1, PBX3, SUPT5H, FOS, MED1, PML, CEBPD, MYB, SMAD1, ZNF3, EVI1, STAT5A, RBM22, SP1, BCL11A, NIPBL, ARID2, REST, ZNF479, ATF7, ASH2L, HNRNPLL, TCF3, MLLT1, NFATC3, MEF2B, FOXA2, MTA3, CREM, HDAC6, NFATC1, PAF1, EBF1, ZNF600, ZBED1, WT1, E2F8, ZSCAN16, MEF2C, TCF7, CDK9, HOXB13, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, NEUROD1, SP140, TCF4, SKIL, GATA3, BATF, MAX, AGO2, ZNF592, SP7, GFI1B, NR2F2, NR2F1, ZNF687, PKNOX1, TP53, MED, ZNF334, NFKB1, BRD2, TBX21, BHLHE40, AR, TAF1, ZBTB40, ZNF366, RB1, MYNN, NCOR1, IKZF2, BRD4, ILF3, RNF2, JUND, CUX1, MAZ, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): AP000295.1,IFNAR1,TMEM50B,IFNAR2,SYNJ1,IFNGR2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 9

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000159082, ENSG00000249624, ENSG00000159110, ENSG00000142166, ENSG00000159128, ENSG00000142188,

eachgene

Deatailed information for cohesin site CDBP00417318