- Basic information
- CohesinDB ID: CDBP00417321
- Locus: chr21-33438470-33439663
-
Data sourse: GSE131606, GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, HCT-116, HSPC, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 57%,
"4_Tx": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: THAP11, POU2F2, ZNF316, MTA3, HDAC6, PAF1, ZFX, NFATC1, SIN3A, ZNF600, ZBTB48, WT1, ZSCAN5A, FOXA1, ZNF770, ZNF563, LEO1, ERG2, HOXB13, ZFHX2, HDGF, ZNF384, RAD21, GRHL3, RXRA, NKX2-1, PAX5, ZNF449, SUPT5H, AGO2, ZNF667, TEAD3, BCLAF1, KMT2A, SCRT2, SUPT16H, SMAD5, ZNF334, EGR2, CTCF, RBM22, BAF155, IKZF5, ZBTB26, PRDM6, MAZ, NFIL3, AHR, ETV4
- Target gene symbol (double-evidenced CRMs): IFNGR2,IFNAR1,TMEM50B,IFNAR2,AP000295.1,SYNJ1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 11
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
ENSG00000159128,
ENSG00000142188,
- Related loop:
chr21:32650000-32675000~~chr21:33425000-33450000,
chr21:32652869-32654298~~chr21:33444420-33446284,
chr21:32825000-32850000~~chr21:33425000-33450000,
chr21:32900000-32925000~~chr21:33425000-33450000,
chr21:32925000-32950000~~chr21:33425000-33450000,
chr21:32939681-32941566~~chr21:33444394-33446526,
chr21:32975000-33000000~~chr21:33425000-33450000,
chr21:33025000-33050000~~chr21:33425000-33450000,
chr21:33175000-33200000~~chr21:33425000-33450000,
chr21:33196199-33197967~~chr21:33444382-33446347,
chr21:33198546-33200679~~chr21:33444546-33446097,
chr21:33199025-33201086~~chr21:33444396-33446544,
chr21:33199028-33200850~~chr21:33444393-33446601,
chr21:33199037-33200983~~chr21:33444394-33446526,
chr21:33199045-33200951~~chr21:33444636-33446481,
chr21:33199050-33200800~~chr21:33443901-33446577,
chr21:33199050-33200857~~chr21:33444407-33446602,
chr21:33199054-33200784~~chr21:33444405-33446286,
chr21:33199054-33200920~~chr21:33444381-33446578,
chr21:33199055-33200924~~chr21:33444392-33446476,
chr21:33199055-33201024~~chr21:33444393-33446535,
chr21:33199058-33200673~~chr21:33444549-33446058,
chr21:33199058-33201037~~chr21:33444352-33446507,
chr21:33199059-33200758~~chr21:33444411-33446307,
chr21:33199061-33200809~~chr21:33443867-33446335,
chr21:33199061-33200994~~chr21:33444395-33446546,
chr21:33199063-33200997~~chr21:33444390-33446463,
chr21:33199064-33200992~~chr21:33444374-33446541,
chr21:33199071-33200963~~chr21:33434105-33435828,
chr21:33199071-33200963~~chr21:33444382-33446347,
chr21:33199073-33200905~~chr21:33444418-33446468,
chr21:33199073-33200975~~chr21:33444374-33446510,
chr21:33199075-33200850~~chr21:33444400-33446333,
chr21:33199075-33200916~~chr21:33444399-33446509,
chr21:33199076-33200916~~chr21:33444431-33446547,
chr21:33199079-33200988~~chr21:33443815-33446553,
chr21:33199079-33200999~~chr21:33443868-33446510,
chr21:33199081-33200983~~chr21:33444401-33446475,
chr21:33199086-33200764~~chr21:33444420-33446284,
chr21:33199087-33200894~~chr21:33444395-33446595,
chr21:33199100-33200791~~chr21:33444407-33446481,
chr21:33199101-33200973~~chr21:33444376-33446489,
chr21:33199111-33200695~~chr21:33444601-33446061,
chr21:33199120-33200900~~chr21:33444450-33446275,
chr21:33199124-33200675~~chr21:33444541-33446079,
chr21:33199126-33200779~~chr21:33444632-33446271,
chr21:33199158-33200692~~chr21:33444614-33446077,
chr21:33199174-33200665~~chr21:33444604-33446075,
chr21:33199181-33200686~~chr21:33444661-33446059,
chr21:33200000-33225000~~chr21:33425000-33450000,
chr21:33214817-33217264~~chr21:33441565-33443170,
chr21:33225000-33250000~~chr21:33425000-33450000,
chr21:33325000-33350000~~chr21:33425000-33450000,
chr21:33360009-33362674~~chr21:33444395-33446546,
chr21:33360017-33362749~~chr21:33444399-33446509,
chr21:33360045-33362734~~chr21:33444390-33446463,
chr21:33360121-33362991~~chr21:33444374-33446510,
chr21:33360130-33362524~~chr21:33444431-33446547,
chr21:33360132-33362704~~chr21:33444396-33446544,
chr21:33360151-33362730~~chr21:33443867-33446335,
chr21:33360153-33362582~~chr21:33444393-33446535,
chr21:33360157-33362875~~chr21:33444546-33446097,
chr21:33360173-33362129~~chr21:33444604-33446075,
chr21:33360203-33362100~~chr21:33444407-33446481,
chr21:33360213-33362978~~chr21:33444400-33446333,
chr21:33360224-33362415~~chr21:33444418-33446468,
chr21:33360228-33362109~~chr21:33444451-33446541,
chr21:33360313-33362104~~chr21:33444549-33446058,