- Basic information
- CohesinDB ID: CDBP00417333
- Locus: chr21-33471801-33472724
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 71%,
"15_Quies": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PHOX2B, BCL11A
- Target gene symbol (double-evidenced CRMs): AP000295.1,IFNAR2,TMEM50B,SYNJ1,IFNAR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000159082,
ENSG00000249624,
ENSG00000159110,
ENSG00000142166,
ENSG00000142188,
- Related loop:
chr21:27500000-27525000~~chr21:33475000-33500000,
chr21:32650000-32675000~~chr21:33450000-33475000,
chr21:32825000-32850000~~chr21:33450000-33475000,
chr21:32925000-32950000~~chr21:33450000-33475000,
chr21:32950000-32975000~~chr21:33450000-33475000,
chr21:33025000-33050000~~chr21:33450000-33475000,
chr21:33050000-33075000~~chr21:33450000-33475000,
chr21:33200000-33225000~~chr21:33450000-33475000,
chr21:33325000-33350000~~chr21:33450000-33475000,
chr21:33350000-33375000~~chr21:33450000-33475000,