- Basic information
- CohesinDB ID: CDBP00417337
- Locus: chr21-33481535-33482250
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 44%,
"5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, ZNF782, FOXA1, RXRB, MLL4, KDM3A, ZBTB7B, HDGF, MEN1, THAP1, ZBTB44, ZNF322, IKZF3, MORC2, ZNF383, PAX5, SFPQ, TEAD1, ZNF121, PITX3, HDAC8, ZNF561, ARID5B, E4F1, SOX5, PAX8, E2F4, DEK, ZNF528, RFX3, KMT2B, GATAD2A, NANOG, ZNF263, POU5F1, TOP2A, BRD3, CTBP1, STAT1, SAP130, ERG, ZBTB21, ZBTB8A, SMARCA4, RFX1, FOXK2, ZNF398, RCOR1, NR2F6, CD74, NFRKB, CEBPB, HNRNPL, CREB1, GABPB1, ZHX2, ELF4, MIXL1, KLF17, ZNF257, GATA2, ZNF644, MXD3, FLI1, HCFC1, MXI1, ZNF785, DRAP1, RELB, EP400, RUVBL2, RUNX1, HDAC1, CEBPA, REPIN1, SP5, TRIM22, SMARCC1, PRDM10, ZBTB2, TFDP1, ELK1, ATF2, FOXM1, SP2, SMARCB1, GMEB1, PML, ZNF331, SMAD1, C11orf30, EVI1, MBD1, ZNF860, ARID2, IKZF5, RBM25, ZSCAN31, AFF1, MBD2, HMGB1, ETV4, NFATC3, MEF2B, ZNF207, CBX3, CREM, CHD2, PAF1, SS18, WT1, MEF2C, CREB3L1, JUNB, NEUROD1, ZFP36, BATF, PLAG1, ZFP69B, BCL11B, ZBTB6, MED, EGR2, ELF3, ARID4B, ZBTB26, HSF1, NCOR1, ILF3, FOSL1, ZNF660, KDM4B, ZNF101, PBX2, HNRNPK, ATF3, THRB, ZFP64, HNRNPUL1, RUNX3, WDHD1, CBFB, ZNF273, TP63, ZSCAN4, ZNF467, INTS11, ELF1, ZNF573, RBM39, KLF10, SMAD5, FUS, CTCF, JUN, ZBTB20, MNT, LMO1, DPF2, RYBP, SIX5, IRF4, ZNF423, ZNF677, ZNF280A, PDX1, TFAP2C, RBPJ, MLX, ZSCAN21, ZBTB17, ZBTB48, ZNF317, MTA2, NONO, SRF, NBN, KDM4A, HOMEZ, ZNF2, FOXP2, RXRA, MIER3, HNRNPH1, VDR, NR3C1, ESRRA, KMT2A, ZBTB11, TBL1XR1, KLF8, GRHL2, ZNF565, EBF3, ZKSCAN5, KDM5A, ZBTB14, SMARCA5, NFIL3, THAP11, EZH2phosphoT487, SOX13, ZNF770, ZMIZ1, ZNF18, SP3, ARNT, BACH1, ZNF48, PRDM9, ZEB2, HMBOX1, NFYA, ETV6, NCAPH2, ZNF10, PBX3, HMGXB4, TEAD3, ZXDB, ZNF680, U2AF1, TAF7, KLF9, TBX5, USF1, BCL11A, SP1, ZNF479, ATF7, ASH2L, CTBP2, GLIS2, SMC3, MLLT1, STAG2, STAG1, ZNF394, SAFB, AGO1, MTA3, EBF1, MAFF, ESR2, ZNF580, ZKSCAN1, KLF7, KDM1A, BCL3, ZNF441, BRG1, ZIC2, PCGF1, GATA3, KLF15, TAL1, ZNF143, AGO2, MTA1, TP53, ZSCAN22, BRD2, PHF5A, KAT8, TBX21, EGR1, RB1, TFIIIC, RNF2, IKZF2, BRD4, JUND, CUX1, ZSCAN23, PGR, CBX5, PATZ1, RING1B, UBTF, TFAP4, SIN3B, CHD7, ZNF444, ATF4, MXD4, ZNF189, SMARCE1, MZF1, RLF, KLF6, NFE2L2, SAP30, ESR1, ZNF217, ZNF524, KLF1, ZNF695, SOX4, E2F6, TRIM24, RFX5, GTF2F1, GLIS1, POU2F2, ZSCAN5D, ZSCAN5A, ZMYND8, ERG2, SP4, TBP, HNF4G, HOXC5, OGG1, SMARCC2, ETS1, MYC, ARID1B, PHF21A, KLF12, NKX2-1, MCRS1, GABPA, STAT3, IKZF1, INO80, DNMT3B, SRSF3, EZH2, ZNF652, MRTFA, PHF8, SPI1, ZNF786, ZNF202, PCBP1, HDAC2, INTS13, GATAD2B, TAF9B, ZNF777, ZNF76, NFYB, ZNF554, ETV5, BCL6, SIN3A, ERG3, CREBBP, ZNF35, ZNF384, RARA, TAF15, NFYC, SMAD4, ZNF518A, ZEB1, ZMYM3, NCOA1, GTF3C2, SREBF2, ZNF22, RBM22, MAFK, HNF4A, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, PPARG, HDAC6, ZNF692, ZNF574, TCF7, FOXO3, RELA, TARDBP, SKIL, MAX, ZNF592, GFI1B, NR2F1, TCF7L2, KDM5B, PKNOX1, ZNF547, ZNF12, AR, KMT2D, ZNF445, YAP1, ZNF324, DMAP1, AHR, FOSL2, ZNF391, HMG20A, HMGN3, MEIS2, SUZ12, RBFOX2, ZFHX2, INSM2, NFIC, ZNF362, CTCFL, PRDM1, KLF14, MECOM, ZNF736, ZNF629, KLF5, BCLAF1, TRIM28, ETV1, RCOR2, USF2, TCF12, BAF155, EP300, SOX6, ZNF512B, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EED, BRD1, MYCN, RUNX1T1, ID3, MLLT3, GATAD1, GMEB2, ARID3A, MIER1, ZNF341, RAD21, GRHL3, APC, XRCC5, ZNF614, NFE2, TCF25, ZNF639, ZNF664, TFE3, HBP1, IRF1, SREBF1, ZGPAT, NAB2, MRTFB, ZC3H11A, MYF5, ATF1, PTBP1, SMC1A, CBX1, SIRT6, ZNF335, ZNF534, ZFX, FIP1L1, SMAD3, TWIST1, IRF2, PRPF4, BRD9, ZSCAN30, GATA4, OSR2, ZNF184, NRF1, CHD1, FOS, SUPT5H, TGIF2, MED1, CEBPD, MYB, SCRT2, VEZF1, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, PHF20, ZBTB7A, CCNT2, PHIP, TCF3, ZNF783, SKI, NELFA, KLF13, FOXA2, RBBP5, E2F8, ZNF600, MIER2, ZBED1, ZBTB33, CDK9, HOXB13, YY1, ZNF148, BRCA1, SP140, ZNF610, HIF1A, OTX2, ZNF519, ZNF449, GATA1, HAND2, CEBPG, SP7, NR2F2, ZNF687, ZNF213, BHLHE40, NFKBIZ, TAF1, ZBTB40, MYNN, NOTCH3, CLOCK, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): DNAJC28,TMEM50B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops