- Basic information
- CohesinDB ID: CDBP00417349
- Locus: chr21-33499516-33501924
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Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE131606
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Cell type: RPE, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
90% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 78%,
"15_Quies": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, GLIS1, ZNF426, SMC1A, ZNF697, TOP2A, PAF1, ZFX, ZNF600, ZMYND11, WT1, ZSCAN5A, ZNF101, ZNF770, ZBTB33, ZNF574, LEO1, HOXB13, ZNF18, MPHOSPH8, NEUROD1, ZBTB8A, NFIC, ZNF266, ZFP64, OSR2, MCM3, GRHL3, PRDM12, OTX2, ZNF781, ZNF518A, ZNF189, SUPT5H, AGO2, NFRKB, ZNF629, THRAP3, ZNF121, ZNF558, ZBTB11, ZXDB, ZNF680, ZNF213, ZNF140, CTCF, RBM22, ZNF577, BCL11A, ZNF664, ARID2, REST, ZNF623, ZC3H11A, ZNF555, ZNF34, AHR
- Target gene symbol (double-evidenced CRMs): CRYZL1,AP000311.1,URB1,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000159128,
ENSG00000249209,
ENSG00000205758,
- Related loop:
chr21:27500000-27525000~~chr21:33475000-33500000,
chr21:29050000-29075000~~chr21:33500000-33525000,
chr21:32325000-32350000~~chr21:33500000-33525000,
chr21:32375000-32400000~~chr21:33500000-33525000,
chr21:33375000-33400000~~chr21:33500000-33525000,
chr21:33500000-33525000~~chr21:33600000-33625000,
chr21:33500000-33525000~~chr21:37150000-37175000,