- Basic information
- CohesinDB ID: CDBP00417356
- Locus: chr21-33514224-33515002
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Data sourse: GSE111537, GSE120943, ENCSR153HNT, GSE98367
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Cell type: K-562, OCI-AML-3, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 72%,
"5_TxWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, POU2F2, SMC1A, CEBPA, TOP2A, PAF1, ZFX, XBP1, ZBTB17, ZMYND11, STAT1, FOXA1, RBFOX2, HOXB13, ZNF300, ERG, RELA, HDGF, ZNF384, JUNB, ATF3, RUNX2, MYC, GRHL3, PBX4, GLYR1, BATF, STAT3, FOS, CDK8, SUPT5H, MED1, CEBPG, CEBPB, JMJD1C, STAT5B, CEBPD, MYB, TERF1, EZH2, ESR1, MLL, OCA2, CTCF, JUN, RBM22, SPI1, AR, IRF1, GATA6, TRIM24, IRF4, BRD4, FOXP1, MAZ, ZIM3, KMT2B, STAG1
- Target gene symbol (double-evidenced CRMs): URB1,CRYZL1,IFNGR2,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000159128,
ENSG00000249209,
ENSG00000205758,
- Related loop:
chr21:29050000-29075000~~chr21:33500000-33525000,
chr21:32325000-32350000~~chr21:33500000-33525000,
chr21:32375000-32400000~~chr21:33500000-33525000,
chr21:33375000-33400000~~chr21:33500000-33525000,
chr21:33500000-33525000~~chr21:33600000-33625000,
chr21:33500000-33525000~~chr21:37150000-37175000,