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Basic information

CohesinDB ID: CDBP00417359

Locus: chr21-33523382-33523959

Data sourse: GSE62063, GSE67783, ENCSR153HNT

Cell type: K-562, HSPC, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 81%, "4_Tx": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF426, ZNF697, SOX2, MEIS2, XBP1, FOXA1, RBFOX2, SRSF4, PBX2, LEO1, HDGF, ATF3, NFIC, ZFP64, ZNF362, ATF4, GLYR1, ZNF189, HDAC3, CDX2, JMJD1C, TRIM28, ZNF573, SNAI2, NFE2L2, SMAD5, ESR1, OCA2, HNF1B, CTCF, JUN, POU2F1, MNT, GATA6, PAX8, DPF2, IRF4, TRIM24, SOX6, DDX20, U2AF2, TEAD4, ZNF555, ZNF175, GATAD2A, PDX1, EED, POU2F2, CHD8, TOP2A, ZNF317, ZBTB17, DUX4, ZBTB48, ZMYND11, STAT1, ZSCAN5A, SAP130, NBN, ERG, MYC, ONECUT1, SMARCA4, EZH1, ARID1B, ZNF180, GRHL3, NKX2-1, GABPA, APC, XRCC5, NKX3-1, NFE2, DNMT3B, DACH1, NR3C1, CEBPB, KMT2A, EZH2, ZNF652, EBF3, NFE2L1, GABPB1, ELF4, SPI1, IRF1, ZNF182, SMARCA5, HCFC1R1, ATF1, RUNX1, MAFG, SMC1A, CEBPA, AFF4, ZFX, ZNF770, ZNF384, EWSR1, CDK6, GATA4, ZNF184, ARNT, BACH1, ZNF781, ATF2, PRDM9, ZEB2, HMBOX1, ZNF518A, ETV6, SUPT5H, CDK8, ZEB1, PML, CEBPD, SCRT2, C11orf30, STAT5A, ZNF22, RBM22, MAFK, BCL11A, USF1, ARID2, REST, ATF7, HOXA9, FOXP1, SMC3, ZNF34, STAG1, ZNF783, ZNF394, FOXA2, AGO1, MTA3, CBX3, PAF1, E2F8, ZNF600, ZSCAN16, GTF2B, MAFF, WT1, ZBTB33, HOXB13, RELA, NEUROD1, HIF1A, OTX2, TAL1, ZNF143, AGO2, GATA1, CEBPG, ZNF592, NR2F2, ZBTB6, PKNOX1, ZNF334, PHOX2B, PAX3-FOXO1, AR, MYNN, NCOR1, NOTCH3, BRD4, JUND, ILF3, ZBTB26, MAZ, ZSCAN23, ZZZ3, ZNF24, ZNF316

Target gene symbol (double-evidenced CRMs): GART,URB1,IFNGR2,AP000311.1,CRYZL1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000142207, ENSG00000159128, ENSG00000159131, ENSG00000249209, ENSG00000205758,

eachgene

Deatailed information for cohesin site CDBP00417359