- Basic information
- CohesinDB ID: CDBP00417373
- Locus: chr21-33548736-33549040
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Data sourse: GSE62063
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Cell type: Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: NIPBL
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 62%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, NME2, FOXA1, HLF, RXRB, HDGF, THAP1, MORC2, PAX5, SFPQ, TEAD1, ZNF121, LMO2, OCA2, HDAC8, E4F1, ZNF157, SOX5, PAX8, E2F4, ZNF674, ZNF528, GATAD2A, POU5F1, ZNF263, TOP2A, CTBP1, ZMYND11, DUX4, STAT1, ZNF134, ZNF485, SAP130, ERG, ZBTB21, EZH1, SMARCA4, RFX1, TOP1, FOXK2, NR2F6, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, ZHX2, ELF4, MIXL1, GATA2, MXD3, SIX2, FLI1, HCFC1, RELB, RUNX1, CEBPA, CRY1, PALB2, TRIM22, SMARCC1, PRDM10, SOX11, ATF2, SMARCB1, PML, TERF1, PIAS1, SMAD1, C11orf30, STAT5A, ARID2, IKZF5, AFF1, HMGB1, NFATC3, CBFA2T2, CBX3, ZNF207, CREM, CHD2, PAF1, NFATC1, ZSCAN16, WT1, MPHOSPH8, NEUROD1, JUNB, PLAG1, KLF4, ZBTB6, BCL6B, RBM14, ELF3, ARID4B, RXR, EGLN2, ZNF366, HSF1, NCOR1, ZBTB26, SCRT1, ILF3, ADNP, ZNF316, FOSL1, XBP1, ZNF101, PBX2, SRSF4, HNRNPK, ATF3, CBFB, TP63, ZSCAN4, MITF, BACH2, MAF, JMJD1C, ELF1, RBM39, SMAD5, CTCF, JUN, MNT, DPF2, IRF4, DDX20, ZNF280A, PDX1, TFAP2C, RBPJ, YBX1, ZNF317, ZBTB17, ZBTB48, ZSCAN21, DDX5, NBN, PHB2, KDM4A, HOMEZ, ZNF2, LHX2, RXRA, NKX3-1, HNRNPH1, VDR, NR3C1, STAT5B, KMT2A, KLF8, EBF3, SSRP1, SMARCA5, NFIL3, THAP11, CTNNB1, SOX13, POU4F2, ZNF770, ZNF513, ZMIZ1, ARNT, BACH1, ZNF48, PRDM9, ZEB2, NCAPH2, ZNF10, MAFB, TEAD3, ZBTB18, USF1, BCL11A, SP1, ZNF479, ATF7, ASH2L, ZFP69, PRDM6, SMC3, STAG1, MLLT1, ZNF394, TRP47, AGO1, MTA3, EBF1, MAFF, ZNF580, ZKSCAN1, BCL3, KDM1A, GATA3, TAL1, NRIP1, ZNF143, AGO2, TP53, ZNF334, ZSCAN22, NFKB1, PHOX2B, BRD2, PHF5A, TBX21, EGR1, TFIIIC, BRD4, JUND, ZSCAN23, CBX5, PGR, ZNF496, SOX2, LEO1, BMI1, ATF4, ZNF189, KLF6, NFE2L2, ESR1, E2F6, TRIM24, GTF2F1, GLIS1, POU2F2, ZSCAN5D, KDM4C, ASH1L, ZSCAN5A, ZMYND8, TBP, HNF4G, OGG1, ETS1, MYC, ARID1B, NKX2-1, GABPA, STAT3, IKZF1, DNMT3B, SRSF3, EZH2, ZNF652, NFE2L1, SPI1, HDAC2, ZNF554, BCL6, SIN3A, ERG3, MYBL2, RARA, ZNF384, CREBBP, ZNF35, TAF15, SMAD4, CDK8, CSNK2A1, ZEB1, ZNF264, ZMYM3, SUPT16H, NCOA1, ZNF22, RBM22, MAFK, HNF4A, REST, HNRNPLL, HOXA9, BCOR, FOXP1, AATF, NCOR2, PPARG, TBL1X, HDAC6, ZNF692, GTF2B, ZNF30, ZNF318, RELA, TARDBP, CHAMP1, ZNF282, SKIL, MGA, MAX, ZNF592, NR2F1, KDM5B, PKNOX1, MYOD1, AR, ZNF445, PAX3-FOXO1, ZNF324, HEXIM1, ZZZ3, AHR, FOSL2, HMG20A, E2F7, ZSCAN5C, HMGN3, MEIS2, RBFOX2, ZNF28, ZNF90, INSM2, NFIC, ZNF362, PRDM1, GLYR1, MECOM, ZNF736, CDX2, ZNF629, ZNF506, THRAP3, KLF5, TRIM28, BCLAF1, USF2, ZFP91, BAF155, EP300, GATA6, SOX6, E2F1, TEAD4, FOXA3, ZNF175, EHMT2, EED, CHD8, BRD1, MYCN, RUNX1T1, ID3, MLLT3, ARID3A, RAD21, GRHL3, APC, XRCC5, ZNF614, NFE2, ZNF639, ARNTL, FEZF1, ZNF664, IRF1, ZGPAT, ZNF766, ZIM3, ATF1, PTBP1, SMC1A, CBX1, MAFG, SIRT6, ZFX, SMAD3, PRPF4, RUNX2, GATA4, OSR2, ZNF184, NRF1, NR2C1, SUPT5H, CHD1, FOS, MED1, CEBPD, SCRT2, ZNF3, L3MBTL2, SETDB1, KLF16, NUP98-HOXA9, NIPBL, ZBTB7A, CCNT2, PHIP, ZNF283, FOXA2, E2F8, MIER2, ZNF600, ZBTB33, CDK9, HOXB13, YY1, SP140, HIF1A, OTX2, ZNF449, GATA1, TLE3, CEBPG, SP7, NCOA3, NR2F2, ZNF512, TAF1, ZNF579, ZBTB42, MYNN, NOTCH3, CLOCK, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): ITSN1,SON,SYNJ1,URB1,PAXBP1,MRPS6,AP000311.1,SLC5A3,IFNGR2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000159082,
ENSG00000159086,
ENSG00000159128,
ENSG00000159140,
ENSG00000249209,
ENSG00000205726,
ENSG00000243927,
ENSG00000198743,
- Related loop:
chr21:29025000-29050000~~chr21:33525000-33550000,
chr21:29050000-29075000~~chr21:33550000-33575000,
chr21:32325000-32350000~~chr21:33525000-33550000,
chr21:32350000-32375000~~chr21:33525000-33550000,
chr21:32725000-32750000~~chr21:33525000-33550000,
chr21:32725000-32750000~~chr21:33550000-33575000,
chr21:32750000-32775000~~chr21:33525000-33550000,
chr21:32750000-32775000~~chr21:33550000-33575000,
chr21:33200000-33225000~~chr21:33550000-33575000,
chr21:33375000-33400000~~chr21:33525000-33550000,
chr21:33375000-33400000~~chr21:33550000-33575000,
chr21:33525000-33550000~~chr21:33675000-33700000,
chr21:33525000-33550000~~chr21:34050000-34075000,
chr21:33550000-33575000~~chr21:33700000-33725000,
chr21:33550000-33575000~~chr21:33800000-33825000,
chr21:33550000-33575000~~chr21:33900000-33925000,
chr21:33550000-33575000~~chr21:34200000-34225000,
chr21:33550000-33575000~~chr21:36350000-36375000,