- Basic information
- CohesinDB ID: CDBP00417409
- Locus: chr21-33633469-33634006
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Data sourse: GSE206145, GSE111913, ENCSR153HNT
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Cell type: K-562, RT-112, HEK293T
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 75%,
"4_Tx": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA2, NKX2-2, POU5F1, TOP2A, CEBPA, ZFX, XBP1, GTF2B, ZSCAN16, FOXA1, ZBTB33, HOXB13, ZNF549, ERG, YY1, MYC, RAD21, GRHL3, RXRA, GABPA, MAX, PAX5, CDK8, CEBPG, CEBPB, PIAS1, SETDB1, ZNF22, CTCF, USF1, SP1, SPI1, HNF4A, AR, GATA2, NCOR1, AHR
- Target gene symbol (double-evidenced CRMs): ATP5PO,URB1,AP000311.1,ITSN1,CRYZL1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 35
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000142207,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
- Related loop:
chr21:32375000-32400000~~chr21:33625000-33650000,
chr21:33625000-33650000~~chr21:33725000-33750000,
chr21:33625000-33650000~~chr21:33800000-33825000,
chr21:33625000-33650000~~chr21:33825000-33850000,
chr21:33625000-33650000~~chr21:33850000-33875000,
chr21:33625000-33650000~~chr21:33875000-33900000,
chr21:33625000-33650000~~chr21:34325000-34350000,
chr21:33625000-33650000~~chr21:34350000-34375000,