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Basic information

CohesinDB ID: CDBP00417411

Locus: chr21-33635325-33635974

Data sourse: GSE206145-GSE177045, GSE67783

Cell type: MCF-7, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 91%, "15_Quies": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXA2, NKX2-2, POU5F1, TOP2A, CEBPA, ZFX, XBP1, GTF2B, ZSCAN16, FOXA1, ZBTB33, HOXB13, ZNF549, ERG, YY1, MYC, RAD21, GRHL3, RXRA, GABPA, MAX, PAX5, CDK8, CEBPG, CEBPB, PIAS1, SETDB1, ZNF22, CTCF, USF1, SP1, SPI1, HNF4A, AR, GATA2, NCOR1, AHR

Target gene symbol (double-evidenced CRMs): URB1,CRYZL1,ATP5PO,SMIM11A,AP000311.1,ITSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 14

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000142207, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000205670,

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Deatailed information for cohesin site CDBP00417411