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Basic information

CohesinDB ID: CDBP00417420

Locus: chr21-33653529-33653858

Data sourse: GSE206145, GSE206145-NatGen2015, GSE86191

Cell type: RPE, Fibroblast, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 69%, "15_Quies": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, ZNF391, BDP1, ZNF426, MEIS2, PATZ1, FOXA1, PBX2, HNRNPK, ATF3, NFIC, ZNF362, CHD7, PRDM1, ZNF189, SMARCE1, ZSCAN4, MITF, CDX2, JMJD1C, ZNF629, KLF5, TEAD1, KLF6, SNAI2, KLF10, ESR1, HNF1B, USF2, JUN, TCF12, CTCF, EP300, GATA6, PYGO2, DPF2, SOX4, RFX5, DEK, E2F1, TEAD4, PDX1, TFAP2C, GLIS1, NANOG, POU5F1, MYCN, ID3, CTBP1, ZSCAN21, ZBTB17, ZBTB48, SRF, NBN, ERG2, ARID3A, TBP, ERG, ZBTB21, HOXC5, MYC, SMARCA4, ZNF2, ARID1B, HOMEZ, RAD21, GRHL3, TSHZ1, RXRA, NKX2-1, STAT3, IKZF1, RCOR1, ZNF639, VDR, ZNF750, ESRRA, CEBPB, NR3C1, CREB1, KLF8, GRHL2, ZHX2, SPI1, ZNF664, EHF, IRF1, KLF17, HDAC2, GATA2, FLI1, MRTFB, NFYB, ZNF554, ZIM3, ATF1, RUNX1, SMC1A, ZBTB24, HDAC1, NKX2-2, ZNF335, ZFX, SIN3A, AFF4, SMAD3, ERG3, CBX8, SMARCC1, PRDM10, MEF2A, CREBBP, ZNF384, ZNF35, RUNX2, GATA4, OSR2, ZNF184, SP3, PBX4, DAXX, ATF2, ZEB2, ZNF518A, HMBOX1, PBX3, FOXM1, SP2, FOS, CDK8, NFYA, MED1, TEAD3, ZEB1, ZXDB, ZNF558, SUPT16H, NR1H2, GTF3C2, TBX5, SETDB1, USF1, BCL11A, NIPBL, SP1, HNF4A, MAFK, REST, ARID1A, RBM25, ATF7, ZHX1, PHIP, GLIS2, FOXP1, AFF1, PRDM6, ZNF623, SMC3, ELL2, STAG2, ZNF394, CBX3, FOXA2, CHD2, PAF1, ZNF600, ZNF692, GTF2B, WT1, MAFF, ZSCAN16, KDM1A, RELA, JUNB, SP140, TCF4, ZNF830, OTX2, GATA3, TAL1, MAX, GATA1, MTA1, PLAG1, KLF4, ZFP69B, SP7, GFI1B, TCF7L2, TP53, PKNOX1, BRD2, ELF3, BHLHE40, AR, ZBTB40, YAP1, ZNF366, NCOR1, RNF2, BRD4, JUND, ZSCAN23, ZNF24, FOSL2

Target gene symbol (double-evidenced CRMs): ITSN1,RCAN1,ATP5PO,AP000311.1,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 27

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000205670, ENSG00000159200,

Tools:

Assay

refGene

Ruler

Cohesin site CDBP00417420

CDBP00417420 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00417420

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