- Basic information
- CohesinDB ID: CDBP00417423
- Locus: chr21-33659609-33660867
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Data sourse: GSE138405, ENCSR153HNT, GSE206145
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Cell type: K-562, Hela-Kyoto, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 39%,
"15_Quies": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CHD8, MAFG, SMC1A, ZFX, POU4F2, MAFF, FOXA1, ZNF205, ZNF770, ERG3, ZNF485, PBX2, PRDM10, YY1, RELA, ZNF384, MYC, ZNF362, ARID1B, PRDM1, HIF1A, BACH1, GATA3, ZNF189, SMARCE1, MAX, MAFB, GATA1, MITF, HNRNPH1, NFE2, PLAG1, NR2F2, ZMYM3, NFE2L2, EZH2, SMAD5, C11orf30, USF2, TBX5, USF1, SPI1, AR, DPF2, HDAC2, GATA2, ZNF182, ZNF777, ZBTB26, RAD51, NOTCH3, MAZ, ZNF316
- Target gene symbol (double-evidenced CRMs): SMIM11A,ATP5PO,RCAN1,AP000311.1,ITSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 36
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
ENSG00000159200,
- Related loop:
chr21:33650000-33675000~~chr21:33750000-33775000,
chr21:33650000-33675000~~chr21:33875000-33900000,
chr21:33650000-33675000~~chr21:33900000-33925000,
chr21:33650000-33675000~~chr21:34350000-34375000,
chr21:33650000-33675000~~chr21:34525000-34550000,