- Basic information
- CohesinDB ID: CDBP00417426
- Locus: chr21-33665960-33666559
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Data sourse: ENCSR153HNT, ENCSR230ZWH, GSE206145-NatGen2015, ENCSR000EDE
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Cell type: K-562, Liver, HeLa-S3, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 45%,
"15_Quies": 45%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, XBP1, FOXA1, PBX2, RXRB, ATF3, ZFP64, PRDM1, ZNF189, MITF, TEAD1, LMO2, RCOR2, MLL, OCA2, PITX3, ESR1, CTCF, EP300, PAX8, TEAD4, TFAP2C, EED, GLIS1, POU2F2, CHD8, RUNX1T1, ID3, CTBP1, ZBTB17, ZBTB48, TBP, ZNF341, MYC, RAD21, GRHL3, RXRA, XRCC5, ZNF614, IKZF1, RCOR1, TERF2, NR2F6, VDR, NR3C1, CEBPB, SPI1, GATA2, CEBPA, AFF4, ZFX, ZNF770, SP5, TWIST1, ZNF384, RUNX2, GATA4, OSR2, PBX4, ARNT, SOX11, PRDM9, SMAD4, FOS, CDK8, MED1, TEAD3, CEBPD, RBM22, BCL11A, SP1, HNF4A, ASH2L, PHIP, PRDM6, SMC3, PPARG, FOXA2, ZNF600, ZNF692, WT1, ZBTB33, YY1, RELA, JUNB, ZFP36, HIF1A, GATA3, NRIP1, ZNF143, GATA1, HAND2, CEBPG, ZFP69B, NR2F2, NFKB1, BRD2, AR, EGLN2, RNF2, BRD4, JUND, ZNF304
- Target gene symbol (double-evidenced CRMs): SMIM11A,AP000311.1,RCAN1,ITSN1,ATP5PO
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 27
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
ENSG00000159200,
- Related loop:
chr21:33650000-33675000~~chr21:33750000-33775000,
chr21:33650000-33675000~~chr21:33875000-33900000,
chr21:33650000-33675000~~chr21:33900000-33925000,
chr21:33650000-33675000~~chr21:34350000-34375000,
chr21:33650000-33675000~~chr21:34525000-34550000,