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Basic information

CohesinDB ID: CDBP00417428

Locus: chr21-33671346-33671816

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 56%, "5_TxWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SOX2, XBP1, FOXA1, HLF, ZFHX2, ATF3, ZBTB44, IKZF3, LMO2, ESR1, HNF1B, USF2, JUN, E2F1, RBPJ, GLIS1, POU2F2, CHD8, BRD3, POU5F1, ZBTB17, ZBTB48, DDX5, ERG2, MYC, SMARCA4, EOMES, RXRA, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, NR3C1, CEBPB, CREB1, EZH2, KLF8, SPI1, GATA2, SMC1A, CEBPA, NKX2-2, ZFX, SMAD3, ZNF770, ERG3, CBX8, RUNX2, GATA4, ZNF184, PBX4, PRDM9, ZEB2, MAFB, MYB, PIAS1, C11orf30, TBX5, RBM22, USF1, BCL11A, NUP98-HOXA9, POU2F3, PHIP, PRDM6, NCOR2, FOXA2, ZNF600, ZSCAN16, WT1, HOXB13, RELA, AHR, SP140, ZFP36, HIF1A, TAL1, SPIB, HAND2, SP7, NR2F1, EGR2, BRD2, AR, ZBTB40, RNF2, BRD4, MAZ, ZNF440, ZNF316

Target gene symbol (double-evidenced CRMs): ITSN1,AP000311.1,SMIM11A,ATP5PO,RCAN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 9

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000205670, ENSG00000159200,

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Deatailed information for cohesin site CDBP00417428