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Basic information

CohesinDB ID: CDBP00417437

Locus: chr21-33692275-33692558

Data sourse: ENCSR000BLD, GSE105028, GSE206145

Cell type: RPE, H1-hESC, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 45%, "5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, HMG20A, SOX2, XBP1, FOXA1, PBX2, ZNF529, CHD7, PRDM1, RUNX3, ZNF189, KLF5, ELF1, TRIM28, ESR1, CTCF, BAF155, SOX5, IRF4, TEAD4, FOXA3, GATAD2A, EED, NANOG, CHD8, POU2F2, BRD3, POU5F1, MTA2, ZBTB17, ZNF317, ZNF134, SP4, HNF4G, ERG, MYC, EOMES, RAD21, RXRA, GABPA, IKZF1, TERF2, NR3C1, ESRRA, FEZF1, SPI1, ZNF257, GATA2, SIX2, FLI1, ZNF490, MRTFB, RUNX1, BCL6, SOX13, ZFP3, CBX8, SMARCC1, RARA, RUNX2, OSR2, GR, ZNF184, ARNT, DAXX, ATF2, PBX3, CDK8, MED1, TEAD3, PIAS1, EVI1, RBM22, SP1, BCL11A, HNF4A, ASH2L, CTBP2, PHIP, BCOR, FOXP1, PRDM6, FOXA2, ZNF207, ZNF600, ZSCAN16, GTF2B, ZNF30, TCF7, CDK9, HOXB13, RELA, BRG1, TCF4, HIF1A, ZIC2, BHLHE22, MAX, ZNF143, SP7, PKNOX1, NFKB1, ELF3, BRD2, T, ARID4B, AR, RXR, ZBTB42, ZBTB26, RNF2, IKZF2, BRD4, MAZ

Target gene symbol (double-evidenced CRMs): SLC5A3,GART,DONSON,SON,ATP5PO,CLIC6,AP000311.1,MRPS6,ITSN1,CRYZL1,RCAN1,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159131, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000205670, ENSG00000159200, ENSG00000159212,

eachgene

Deatailed information for cohesin site CDBP00417437