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Basic information

CohesinDB ID: CDBP00417439

Locus: chr21-33695730-33696319

Data sourse: GSE126634, GSE152721, ENCSR917QNE

Cell type: Liver, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 42%, "5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NANOG, SMC1A, POU2F2, FOXA2, NKX2-2, POU5F1, BRD3, SOX2, ZFX, ZNF600, XBP1, ZBTB17, ZNF534, GTF2B, FOXA1, ZNF770, CBX8, DDX5, PBX2, SP4, SMARCC1, ZNF318, ERG, ZNF792, RELA, ZNF596, ZNF133, JUNB, MYC, RUNX2, GATA4, ZNF362, ONECUT1, CHD7, PRDM1, GRHL3, HIF1A, RXRA, GATA3, GABPA, STAT3, ZNF354A, TAL1, ZNF143, GATA1, NR3C1, TEAD1, ZNF573, TP53, ZBTB6, OCA2, KLF9, ESR1, TBX5, MYOD1, CTCF, RBM22, JUN, SPI1, NUTM1, ZNF695, HNF4A, ZFP28, GATA6, AR, LMO1, NKX2-5, GATA2, REST, SIX2, POU2F3, FLI1, RNF2, BRD4, PHIP, PRDM6, ZIM3, PDX1

Target gene symbol (double-evidenced CRMs): SON,ATP5PO,GART,DONSON,RCAN1,AP000311.1,CRYZL1,SLC5A3,SMIM11A,ITSN1,MRPS6,CLIC6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 36

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159131, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000205670, ENSG00000159200, ENSG00000159212,

Tools:

Assay

refGene

Ruler

Cohesin site CDBP00417439

CDBP00417439 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00417439

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