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Basic information

CohesinDB ID: CDBP00417442

Locus: chr21-33701558-33702121

Data sourse: GSE206145-GSE177045, GSE67783, GSE111913, GSE62063, GSE120943

Cell type: MCF-7, Monocytes, RT-112, HSPC, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: NIPBL,SA1,Mau2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 65%, "5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ASCL1, CEBPB, ZNF341, NEUROD1, ONECUT1, BRD3, PAX8, ZFX, ARNT, RXRA, OTX2, FOXA1, CLOCK, TBX5, DDX5, ZSCAN4, ZNF143

Target gene symbol (double-evidenced CRMs): DONSON,RCAN1,CRYZL1,MRPS6,AP000311.1,HUNK,ITSN1,ATP5PO,SLC5A3,SON

Function elements

Human SNPs: .

Number of somatic mutations (coding): 27

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142149, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000159200,

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Deatailed information for cohesin site CDBP00417442