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Basic information

CohesinDB ID: CDBP00417444

Locus: chr21-33704920-33705073

Data sourse: ENCSR000BKV

Cell type: K-562

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 76%, "5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, XBP1, FOXA1, UBTF, THAP1, PRDM1, ZNF189, TP63, ZNF320, TEAD1, TRIM28, ESR1, OCA2, CTCF, SMC1, GATAD2A, TFAP2C, EED, GLIS1, CHD8, ZSCAN5D, POU5F1, ZBTB48, DDX5, TBP, ERG, ETS1, MYC, RAD21, GABPA, APC, XRCC5, STAT3, CREB1, EZH2, IRF1, ZNF182, ZIM3, ETV5, RUNX1, ZNF585A, BCL6, HDAC1, NKX2-2, POU4F2, SMAD3, CBX8, ERG3, ZNF133, RUNX2, ARNT, HMBOX1, MAFB, TEAD3, NCOA1, RBM22, BCL11A, ASH2L, FOXP1, ELL2, TRP47, PPARG, FOXA2, TBL1X, ZSCAN16, WT1, HOXB13, YY1, RELA, SP140, HIF1A, OTX2, ZNF143, GATA1, KDM5B, TP53, PHOX2B, ELF3, AR, EGLN2, ZBTB26, NOTCH3, BRD4, AHR

Target gene symbol (double-evidenced CRMs): ITSN1,RCAN1,ATP5PO,SON,SLC5A3,CRYZL1,AP000311.1,MRPS6,DONSON,HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 9

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142149, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000159200,

Tools:

Assay

refGene

Ruler

Cohesin site CDBP00417444

CDBP00417444 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00417444

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