- Basic information
- CohesinDB ID: CDBP00417448
- Locus: chr21-33711416-33711912
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Data sourse: GSE98367, GSE120943, ENCSR230ZWH, ENCSR917QNE
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Cell type: Liver, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
88% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 60%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NME2, XBP1, FOXA1, HLF, CHD7, RUNX3, PRDM1, ZSCAN4, ZNF26, SNAI2, JUN, TCF12, BAF155, LMO1, PAX8, IRF4, GATAD2A, NANOG, CHD8, TOP2A, RUNX1T1, CDK7, NBN, HNF4G, ERG, MYC, SMARCA4, ARID1B, RAD21, RXRA, GABPA, NKX3-1, ZNF639, NR3C1, CEBPB, CREB1, EZH2, SPI1, GATA2, RUNX1, ZNF404, CEBPA, ZFX, ZNF384, NOTCH1, RUNX2, ZNF184, ARNT, ATF2, SUPT5H, CHD1, MED1, MYB, SCRT2, PIAS1, SMAD1, NUP98-HOXA9, RBM22, SP1, BCL11A, HNF4A, ARID1A, ASH2L, PHIP, FOXP1, FOXA2, ZNF692, ZBTB33, CDK9, HOXB13, YY1, RELA, BRG1, TCF4, TAL1, MAX, NRIP1, TLE3, ZFP69B, NR2F2, ZNF544, BRD2, AR, NOTCH3, BRD4, JUND, SCRT1
- Target gene symbol (double-evidenced CRMs): DONSON,MRPS6,ATP5PO,HUNK,CRYZL1,SON,SLC5A3,RCAN1,AP000311.1,ITSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
ENSG00000159200,
- Related loop:
chr21:31950000-31975000~~chr21:33700000-33725000,
chr21:33550000-33575000~~chr21:33700000-33725000,
chr21:33575000-33600000~~chr21:33700000-33725000,
chr21:33700000-33725000~~chr21:33875000-33900000,
chr21:33700000-33725000~~chr21:33900000-33925000,
chr21:33700000-33725000~~chr21:34100000-34125000,
chr21:33700000-33725000~~chr21:34200000-34225000,
chr21:33700000-33725000~~chr21:34250000-34275000,
chr21:33700000-33725000~~chr21:34325000-34350000,
chr21:33700000-33725000~~chr21:34525000-34550000,
chr21:33700000-33725000~~chr21:34600000-34625000,