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Basic information

CohesinDB ID: CDBP00417449

Locus: chr21-33712966-33713558

Data sourse: ENCSR000BLD, GSE206145-NatGen2015, GSE67783

Cell type: H1-hESC, Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: False

Compartment: 88% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 51%, "5_TxWk": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NME2, XBP1, FOXA1, HLF, CHD7, RUNX3, PRDM1, ZSCAN4, ZNF26, SNAI2, JUN, TCF12, BAF155, LMO1, PAX8, IRF4, GATAD2A, NANOG, CHD8, TOP2A, RUNX1T1, CDK7, NBN, HNF4G, ERG, MYC, SMARCA4, ARID1B, RAD21, RXRA, GABPA, NKX3-1, ZNF639, NR3C1, CEBPB, CREB1, EZH2, SPI1, GATA2, RUNX1, ZNF404, CEBPA, ZFX, ZNF384, NOTCH1, RUNX2, ZNF184, ARNT, ATF2, SUPT5H, CHD1, MED1, MYB, SCRT2, PIAS1, SMAD1, NUP98-HOXA9, RBM22, SP1, BCL11A, HNF4A, ARID1A, ASH2L, PHIP, FOXP1, FOXA2, ZNF692, ZBTB33, CDK9, HOXB13, YY1, RELA, BRG1, TCF4, TAL1, MAX, NRIP1, TLE3, ZFP69B, NR2F2, ZNF544, BRD2, AR, NOTCH3, BRD4, JUND, SCRT1

Target gene symbol (double-evidenced CRMs): DONSON,RCAN1,SON,ATP5PO,SLC5A3,CRYZL1,AP000311.1,HUNK,MRPS6,ITSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 54

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142149, ENSG00000159140, ENSG00000159147, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000159200,

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Deatailed information for cohesin site CDBP00417449